Báo cáo y học: "What is the best site for central venous catheter insertion in critically ill patients" doc
Báo cáo y học: "What is the best site for central venous catheter insertion in critically ill patients" doc
... at increased risk for pulmonary complications(severe emphysema, acute respiratory distress syndrome)were not included in the analysis – a fact that may explainthis surprising finding. In a ... catheters) [1], malposition was significantlyCommentaryWhat is the best site for central venous catheter insertion in critically ill patients?Jean-François TimsitRéanimation médicale et infectieuse, ... only 17 wereincluded in the meta-analysis. The meta-analysis populationincluded ICU and non-ICU patients, and no distinction wasmade between catheters inserted for dialysis, pulmonaryartery...
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Báo cáo y học: "What is the clinical and ethical importance of incidental abnormalities found by knee MRI" docx
... However, this is the first study in this area.Our findings raise issues for the planning of studies and ethi-cal issues related to the obligation of the physician-researcherto study participants ... Technicians trained in the measurementand scoring of structural change read the MRI scans: they arenot usually trained in musculoskeletal radiology or MRI beyond the measurements they perform. The researcher ... This is asignificant ethical benefit in longitudinal studies that requirerepetitive imaging of healthy subjects. MRI is thus being usedincreasingly for the imaging of joints for both clinical...
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Báo cáo y học: "What is the role of surfactant and inhaled nitric oxide in lung transplantation" pps
... laboratory investigations [8]. Therefore, manylung transplant programmes use iNO routinely during earlyreperfusion of the lung. Bearing in mind that the concept ofischaemia/reperfusion injury in clinical ... and do these findings apply toother forms of lung injury?Ischaemia/reperfusion injury leading to initial graft failure is amajor cause of early mortality after lung transplantation. In addition, ... be successful in experimental severe reperfusion injury [15], strengthening the hypothesis that this combination prevents intrapulmonaryshunt more effectively than does either intervention alone,and...
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Báo cáo y học: "Plasma DNA concentration as a predictor of mortality and sepsis in critically ill patients" pptx
... necrosis and apop-tosis, the sepsis is associated with many other forms of cellularstress [14], allowing for active secretion as a potential thirdmechanism in this scenario.Interestingly, in ... about 3 hours, making the test a potentially realistic anduseful one in the clinical setting (when predicting outcomeearly in the course of a disease process). Finally, we used the SOFA score ... provided the original work is properly cited.AbstractIntroduction Risk stratification of severely ill patients remainsproblematic, resulting in increased interest in potentialcirculating markers,...
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Báo cáo y học: "Conceptual issues specifically related to health-related quality of life in critically ill patients" pps
... functional ability may sometimes be the onlyway to determine baseline HRQOL.Response shift in critically ill patientsPatients become accustomed to their illness. An importantmechanism in this adaptive ... raised the possibility ofscoring patients at risk before discharging them home,assessing their recovery environment and ensuring thatpatients are assessed at the critical care follow-up clinic.Schelling ... of the study, contributed to the interpretation of the data and revised the manuscript for important intellec-tual content. AJPS contributed to the interpretation of the data and revised the...
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Báo cáo y học: "Multiple-center evaluation of mortality associated with acute kidney injury in critically ill patients: a competing risks analysis" pdf
... prospectively collected on a daily basis bysenior physicians of the participating ICUs who are clo-sely involved in establishing the database. For all patients,information is recorded at baseline (including ... Thus, censoring is clearly informative (that is, the survival time of an individual does depend on cen-soring). In other words, informative censoring defines acompeting risk, given that discharge ... used in the ICU setting. By applying sucha model, this study confirms that AKI affecting criticall y ill patients is associated with increased mortality. How-ever, further investigations focusing...
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Báo cáo khoa học: " A Clinical relevance of Aspergillus isolation from respiratory tract samples in critically ill patients" docx
... fumigatuscan invade the pulmonary parenchyma, resulting in invasivepulmonary aspergillosis, a disease with a high lethality. Morerecently, a locally invasive form called necrotizing pulmonaryaspergillosis ... defined by the EuropeanOrganisation for the Research and Treatment of Cancer/Mycoses Study Group (EORTC/MSG), is difficult to establish in critically ill patients. The aim of this study is ... risk factors. The golden standard for the definite diag-nosis of proven invasive pulmonary aspergillosis remainshistopathological lung tissue examination. In clinical practice, the diagnosis...
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Báo cáo y học: " Determination of the relative amounts of Gag and Pol proteins in foamy virus particles" doc
... after packaging [4]. It may, there-fore, be surprising not to find equal amounts of the twosubunits in virions. The reason for this is presentlyunclear. It may be that different blotting efficiencies ... only the relative Gag to Pol ratios. How can this find-ing be explained in the light of recent results in which twodistinct RNA structures were identified to be essential for Pol protein incorporation ... strategy.One of the central features of Spumaretrovirinae, which dis-tinguishes them from Orthoretrovirinae, is the expressionof a Pol precursor protein independently of the Gag pro-tein from a spliced...
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Báo cáo y học: "Inhalation with Fucose and Galactose for Treatment of Pseudomonas Aeruginosa in Cystic Fibrosis Patients"
... hypothesized that P. aeruginosa lung infection should be cleared by inhalation of fucose and ga-lactose, which compete for the sugar binding site of the two lectins and thus inhibit the binding ... fluid. As this elevator is driven by the beating of the cilia, their inactivation would also facilitate the infection, which is indeed the case as these two lectins also im-mobilise the cilia, ... may be developed by interfering with the bacterial attachment to the airway epithelium. P. aeruginosa produces two lectins, carbohydrate binding proteins, designated P. aeruginosa lectin...
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Báo cáo y học: " Impact of delayed admission to intensive care units on mortality of critically ill patients: a cohort study" pot
... benefits critically ill patients.Key messages• Demands for ICU beds are increa sing worldwideand delay to ICU admission is becoming a more fre-quent issue.• Thereisanincreaseinmortalityforeachhourofdelay ... 44.8%).Analysis of the delay to ICU admission by multivariateanalysis is presented in Table 3. Each w aiting hour wasassociated indepe ndently with a 1.5% increase in risk ofICU mortality (hazard ... Assessment in the first day ofICU stay; SOFA: Sequential Organ Failure Assessment; TISS 28 D1:Therapeutic Intervention Scoring System 28 in the first day of ICU stay; TISS28: Therapeutic Intervention...
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