Báo cáo khoa học: "The influence of the PRKAG3 mutation on glycogen, enzyme activities and fibre types in different skeletal muscles of exercise trained pigs" pot

... Granlund et al.: The influence of the PRKAG3 mutation on glycogen, enzyme activities and fibre types in different skeletal muscles of exercise trained pigs. Acta Veterinaria Scandinavica2011 53:20.Submit ... 0.05) in the carriers of the PRKAG3 mutation than in the non-carriers only in m. longissimus dorsi, and there was no differencebetween genotypes regarding HAD activity in any of the muscles. The ... Veterinaria Scandinavica 2011, 53:20http://www.actavetscand.com/content/53/1/20Page 7 of 8RESEARCH Open Access The influence of the PRKAG3 mutation on glycogen, enzyme activities and fibre types...

Báo cáo khoa học: Mechanism for transcriptional synergy between interferon regulatory factor (IRF)-3 and IRF-7 in activation of the interferon-b gene promoter docx

... combination of proteins by the value obtainedwhen the fold induction for e ach of the proteins present in the combination were added (Table 1). There was littlesynergy i n the absence of cotransfected ... strongly to the N-, C1- and C2-regions of p300, and to the N- and C2-regions of CBP. Thus, the bulk of the interaction between NF-jB and p300/CBP is mediated by the p65 subunit through the N- and ... an bind to p300 and CBP through multiple domains, with a preference of c-Junfor the N- and C-terminal regions and of ATF-2 for the central region of the coactivators.Binding of p50 (amino acids...

Báo cáo khoa học: " A geminiviral amplicon (VA) derived from Tomato leaf curl virus (ToLCV) can replicate in a wide variety of plant species and also acts as a VIGS vector" pps

... the null mutation in the AC2 ORF of the VIGSleads to enhanced silencing of PCNA, thus increasing the efficiency of the VIGS vector.Results and DiscussionConstruction of Viral Amplicon (VA) ... indicated on the top of CR-region. (B) The map of the viral amplicon cloned in pCAMBIA1391Z vector backbone (designated as VA/pCAMBIA1391Z), where the positions of the cloned fragments and of the ... As shown in Fig. 1A, the minimal repliconturned out to be the CR-AC3 segment and the CR alongwith the AC1 component of this segment was the mostvital region. Mutation and deletion in the AC3...

báo cáo khoa học: "Gastrointestinal stromal tumors: correlation between symptoms at presentation, tumor location and prognostic factors in 47 consecutive patients" pot

... all the GI tract: 50-70% in the stomach, 25-30% in the small intestine, 5-10% in the colon-rectum, < 5% in th e esophagus, the remainingmay a rise within the omentum or within the peritonellayers ... processing was obtained with formalin fixation fol-lowed by paraffin inclusion, 3 μm sectioning, and staining with he matoxylin and eosin. Morphologicappearance and cellular descriptions referred ... from interstitial cell of Cajal, or their related stem cells. The mostcommon clinical presentation of these tumors is gastrointestinal bleeding, otherwise they may cause intestinalobstruction,...

Báo cáo khoa học: "Medical treatment for the terminally ill: the ‘risk of unacceptable badness’"

... loadedquestions in their quest for end -of- life decisions. Forexample, ‘This is your grandmother’s 17th transfer from askilled nursing facility in 3 months for sepsis and respiratory failure, and now ... with strong familialincentives to tread the path of least resistance in end -of- lifecare is twofold. First, in end -of- life issue discussions, we muststrive for ‘consensus without consent’ [15]. ... Discussions withsurrogates should strive for concordance and understandingbut not extend to soliciting their consent for medicallyinappropriate care. They simply should not be offeredinappropriate...

Tài liệu Báo cáo khoa học: Dmrt1 genes at the crossroads: a widespread and central class of sexual development factors in ﬁsh pdf

... the ﬁsh gonads The developmental expression of dmrt1 has been wellstudied in the context of gonadal induction and main-tenance, illuminating its important function. But whatabout the other dmrt ... regu-lators of germ cell proliferation.ConclusionTo conclude, it seems that the longstanding hypothesissuggesting that the molecular sequence of sex-determi-nation cascades might disobey the conventional ... particularly in the context of early gonadaldevelopment, gonadal differentiation and sex change.This minireview aims at distilling current knowledgeabout the expression and regulation of dmrt1s in ﬁshtowards...

Tài liệu Báo cáo khoa học: Nucleolin/C23 mediates the antiapoptotic effect of heat shock protein 70 during oxidative stress pptx

... lost.Taken together, our results demonstrate an impor-tant relationship among the regulation of nucleo-lin ⁄ C23, the activation of caspase-3 and the induction of apoptosis under the setting of oxidative ... centrifugation(10 000 g, 1 min, 4 °C), the protein concentration in the supernatant was determined using the BioRad proteinassay. Supernatants containing equal amounts of protein(corresponding to ... 1C).Increased nucleolin/C23 protein levels in Hsp70-transfected cells in response toH2O2-induced apoptosisWe next examined the expression of nucleolin ⁄ C23protein in these cells in response...

Tài liệu Báo cáo khoa học: MicroRNA-23a promotes the growth of gastric adenocarcinoma cell line MGC803 and downregulates interleukin-6 receptor pdf

... elevate the EGFP intensity in the reporter vectors containing mutations of the second or third miR-23a binding regions. (C) Similarly, overexpression of miR-23a failed to suppress the EGFP intensity ... interacts with the ﬁrst potential binding site of the IL6R mRNA 3¢ UTR. (A) The three EGFP reporter vectors bear-ing mutations of the miR-23a seed region binding site are shown. The arrows indicate ... vectors containing the mutations of the miR-23a binding site (Fig. 4A). It was shown thatmiR-23a ASO or pcDNA3 ⁄ pri-23a did not affect the intensity of EGFP ﬂuorescence in the vector bearingthe...

Tài liệu Báo cáo khoa học: Structural insights into the substrate speciﬁcity and activity of ervatamins, the papain-like cysteine proteases from a tropical plant, Ervatamia coronaria ppt

... here.Modes of binding of E-64 with ervatamin-A and ervatamin-C The modes of binding of E-64 with ervatamin-A and ervatamin-C have been analyzed and compared with the structures of other complexes of the ... distributions, respectively. The sigmoidal shape of the dis-tribution of the acentric reﬂections (black continuous) indicates poten-tial twinning. (B) Estimation of the twin fraction a from a Britton ... difference in the orientation of the P3 moiety is further in uenced by the different orienta-tion pattern of the individual P2 Leu residues. In erva-tamin-A, the P3 moiety of both the molecules of the asymmetric...

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