... engendered by the
widely publicized infectious hazards of the transfusion of blood
products. This underlying trepidation, spanning continents and
cultures [15–17], spurred the careful examination of blood
transfusion ... physicians will never view
transfusion of blood and blood products in quite the same way.
Competing interests
None declared.
Acknowledgments
Supported by gr...
... ventilator.
Now, after years of clinical experience with mechanically
ventilated patients, I always look at the patient’s inspiratory
effort and the ventilator delay to check whether there may be
problems ... [4,5].
The clinically important thing was that, with any approach, we
were able to monitor the improvement in the patient´s
condition by examining the delay between the start of
insp...
... can be
formed. The ability to identify reliable surrogates of
immunity (possibly in vivo assays of CD8
+
T-cell medi-
ated cytotoxicity) will be crucial to the testing of novel
vaccine candidates. ... http://respiratory-research.com/content/2/3/157
commentary
review
reports primary research
Respiratory Research Vol 2 No 3 Schluger
whole cascade of inflammatory events. On the other han...
... sinus surgery would be extremely
difficult to demonstrate because the incidence of
serious complications is, fortunately, already very
low. Image-guided surgery has not yet, and may
never, become ... sinonasal anatomy and
physiology which are well covered elsewhere and
beyond the scope of this review.
1,2
Diagnostic Considerations
Prior to beginning a discussion of surgical man-
agement...
... generally focused on the activity of the
cyclo-oxygenases, of which there are two isoforms: cyclo-
oxygenase (COX)-1 and COX-2 (for review, see Smith and
coworkers [65]). COX-1 is constitutively expressed ... JG, Nusing RM, Fritz P:
Expression of cyclooxygenase 1 and cyclooxygenase 2 in
human synovial tissue: differential elevation of cyclooxyge-
nase 2 in inflammatory joint diseases....
... play a part, but that
moves beyond the scope of this review.
People also vary in their ability to cope and their health
beliefs. It has been hypothesized that small beneficial effects
from psychosocial ... among psychosocial and other factors potentially
associated with arthritis pain, disability, and quality of life.
This paper is structured in two parts. It begins with an
overview of...
... [73,74].
Eliminating TNFα by antibody therapy might therefore be
beneficial not only by directly suppressing proinflammtory
processes but also by restoring the suppressive function of
Treg cells.
Nadkarni ... the synovium of patients with
RA and considered of importance in the migration of cells to
the synovium (reviewed in [20]). A recent study by Kop and
colleagues show that neutral...
... our knowledge of the
pivotal role played by cytokines during the effector stages of
human disease; has been instrumental in clarifying the place
of cytokines in the maintenance and chronicity ... stimula-
tion, as is often seen with exhausted lymphocytes, remains
possible. Lymphocytes are scattered in the synovial sublining
layer, and T cell-derived cytokines, with the exception of...