... scavenging, upregulation of heme oxygenase-1. Toxicology: pulmonary irritant, mitochondrial poisonInflammatory effects Dose-dependently proinflammatory or anti-inflammatory and anti-apoptotic effectsTable ... mecha-nism of H2S toxicity [4,5]. During recent years, however, H2Shas been recognized as an important signaling molecule of the cardiovascular system, the inflammatory system and the nervous system. ... sources Synthesized in various tissues from L-cysteine by cystathionine-β-synthase or cystathionine-γ-lyasePharmacological inhibitorsD,L-propargylglycine and β-cyanoalanine (limited selectivity,...