... majority of the
mechanical strain in the asthmatic airway during a DI is
taken up by increased extensibility of the extracellular
matrix, by the intracellular series elastic component, or by
the ... of
narrowing that can be attained in the healthy airway during
maximal bronchial provocation [5–8]. The static elastic
load against which the muscle must shorten is appre...
... monitor and explore organizational con-
text over the five years in 36 nursing homes in the Cana-
dian provinces of Alberta, Saskatchewan, and Manitoba.
Structural facility and unit-level data ... quanti-
tative data about the same phenomenon; emphasizing
how qualitative findings link to and confirm quantitative
findings, as well as how quantitative findings inform
qualitative fin...
... mon-
telukast. The currently available pharmaceutical
armamentarium for the management of asthma is
actually quite good. Appropriate and particularly
early use of anti-inflammatory strategies (in addi-
tion ... previously reviewed,
1
pharmacotherapy for
asthma has changed dramatically in the past 100
years. At the turn of the century, therapy for
acute asthma included mainly narc...
... by almost all cell
types and participate in the inflammatory cascade that
occurs in airways.
142
PGs D
2
,E
2
, and F
2
have a variety of
effects on airway physiology, including polarizing immune
cells ... fibrosis and remodeling in the
airway via inhibition of certain matrix metalloproteinases
(MMPs). Clinically, PDE
4
inhibitors reduce early and late
inflammatory response...
... prehospital airway management. In scenario B,
the manikins were placed on the ground abutting a wall,
and access to the manikin head and airway was from the
caudal end only. This setting was arranged ... Kongstad P, Kurola J, Nakstad AR, Sandberg M: Pre-
hospital airway management: guidelines from a task force from the
Scandinavian Society for Anaesthesiology and Inten...
... Tan A, Iasvovskaia S, et al. Ras and mitogen-activated
protein kinase kinase kinase-1 coregulate activator protein-1- and
nuclear factor-kappaB-mediated gene expression in airway epithe-
lial ... maternal smoking is the primary causal factor
in the changing prevalence of asthma, we are proposing that
it is an important contributing factor, with significant
potential to interact w...
... devel-
oped. All measurements from the single-antigen ELISAs were
combined with the measurements from the bead-array
cytokine assay for integrated analysis of cytokine and autoan-
tibody profiles in baseline ... x values, actual cytokine concentrations; y values, an artificial noise value was added to achieve better visual separation of the actual
cytokine values. P values are...
... (GIH), Luhya in Webuye, Kenya
(LWK), and Toscani in Italy (TSI), to create a final data-
set containing 722 individuals from 12 populations.
After merging the HapMap and the so uth Indian data
sets, ... Asian populations while the HapMap
GIH and the Brahmin show a closer relationship to
HapMap European populations. The Mala/Madiga and
Yadava show a similar distance to...
... primary site and phenotypically show up at
secondary sites [5]. Kaplan et al.alsoshowedthatcan-
cer cells in murine models may relay signals, involving
vascular endothelial growth factor recep tor ... metastasis occurs
early in the life cycle of carcinogenesis. P odsypanina et
al. engineered untransformed mouse mammary cells to
express inducible oncogenes transgenes that are able to...
... data, the developing analysis and
further sampling and interviews. Data generation continued until thematic saturation
was achieved. In reporting the final analysis the data are presented to ... designed the study, led the analysis and wrote the paper. EP conducted the
interviews and the initial analysis and contributed to the drafting of the manuscript. FL
was p...