... group) of 4 μM nitric oxide. In two further series, the glycocalyx was enzymatically degraded by heparinase, applied into the coronary system in the course of ischemia, fol-lowed again by reperfusion ... group), in the presence of 4 μM NO (NO group),and after the glycocalyx had been enzymatically degraded bymeans of heparinase (10 U of enzyme in a volume of 1.5 mLapplied into the coronaries in the ... findings, there is little doubt that degradation of the endothelial glycocalyx leads to impaired regulation of organblood flow, to activation of coagulatory and inflammatory path-ways, and to...