... 5-bromo-4-chloroindol-3-yl phosphate;CD, celiac disease; Ep, epitope; GP, guinea-pig; IPTG, isopropylthio-b-D-galactoside; scFv, single-chain antibody fragment;TMB, 3,3¢,5,5¢-tetramethylbenzidine ... asexamples. To avoid interference due to the differentaffinities of the antibodies for the antigen, the A valuescorresponding to interaction with full-length tTG have beenset to 100 and the A values for ... recognized by these anti-bodies as being conformational and located in the core do-main of the enzyme. This is identical to the region recognizedby anti-transglutaminase Igs found in the serum of celiacdisease...