Báo cáo y học: " Potent anti-inflammatory and antinociceptive activity of the endothelin receptor antagonist bosentan in monoarthritic mice" ppt

... targetfor therapeutic intervention in RA. We therefore exam-ined the effects of endothelin receptor antagonists on the inflammation and inflammatory pain during the course of murine antigen-induced ... Imhof et al.: Potent anti-inflammatory and antinociceptive activity of the endothelin receptor antagonist bosentan in monoarthritic mice. Arthritis Research & Therapy 2011 13:R97.Submit your ... 7 of 9any detectable anti-inflammatory or antinociceptive activity. Effect of bosentan on antigen-induced arthritis flare-upreactionsGiven the potent anti-inflammatory and antinociceptive activity...

Báo cáo y học: " Ageing, autoimmunity and arthritis: Senescence of the B cell compartment — implications for humoral immunity" pptx

... Ageing of lymphocytes and lympho-cytes in the aged. Immunol Today 2000, 21:515-521.55. Timm JA, Thoman ML: Maturation of CD4+lymphocytes in the aged microenvironment results in a memory-enriched ... http://arthritis-research.com/content/6/4/131IntroductionDuring the past decade the number of laboratoriesinvestigating immune senescence has increased dramati-cally, rapidly advancing our understanding of how the immune systems of ... age.Historically, aging has been thought of as a state of immune deficiency. Elderly individuals present withincreased susceptibility to, and severity of, infectiousdiseases and decreased vaccine efficacy....

Báo cáo y học: "Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureu" pot

... Figure S3 in Additional file 1); and twoother enzymes are partially inhibited, CYP2C19 onlyslightly (5% loss of activity) and CYP2D6 moderately(40% loss of activity) .Human cells and staphylococcal ... and acetyl-CoA synthetase (6.2.1.1) as well as enzymesinvolved in the conversion of acetyl-CoA to L-valine and the conversion of serine to cysteine.Annotation of metabolic enzymes and flux ... isoquinoline; IQ-143: synthetic analogue of the novel-type N:C-coupled naphthyl-isoquinoline alkaloid ancisheynine; KEGG: KyotoEncyclopedia of Genes and Genomes; OD: optical density; PCR: polymerasechain...

Báo cáo y học: "Combined adenocarcinoid and mucinous cystadenoma of the appendix: a case report" pdf

... Mucinouscystadenoma is the commonest of the benign neoplasms of the appendix, with an incidence of 0.6% in appendicectomy specimens. We report a rare combination of these tumours and discuss the latest ... publication of this case report and any accompanyingimages. A copy of the written consent is available forreview by the Editor -in- Chief of this journal.Competing interests The authors declare that they ... purposes)CEA, cytokeratin, lysozyme, chromogranin A, serotonin and synaptophysin. Goblet cell carcinoids have increasedexpression of NAP1L1, MAGE-D2, and MTA-1 genes com-pared with benign carcinoids....

Báo cáo toán học: "Chemical composition and antibacterial activity of the essential oils from Launaea resedifolia L." docx

... 24 h. The antibacterial activity was assessed by measuring the zone of growth inhibition surrounding the disks. Each experiment was carried out in triplicate [16]. The minimal inhibitory concentration ... al. [6]. In continuation of our phytochemical and antibacterial studies of the Algerian Sahara medicinal plants [7–11], we report here the findings of our studies on the composition and antimicrobial ... using diethyl ether. The resulting extract was dried on anhydrous sodium sulphate. Diethyl ether was removed carefully and the essential oil was collected and stored at 4°C until analysis. The...

báo cáo hóa học:" Chemical composition and antibacterial activity of the essential oils from Launaea resedifolia L." potx

... noteworthy that the results of this study may be considered as the first report on the composition of the essential oils of this endemic species. 2.6. Antimicrobial activity The quantification of ... identified using the ordinary GC-MS technique to reveal the presence of 19 compounds dominated anhydrous sodium sulphate. Diethyl ether was removed carefully and the essential oil was collected and ... constituent in visible parts was Dioctyl phthalate (39.84%) and the yield of essential oils was 0.9%. These extracts reveal in vitro antibacterial activity on the studied bacterial, confirmed by the inhibition...

Báo cáo hóa học: " Chemical composition and antibacterial activity of the essential oils from Launaea resedifolia L" pdf

... identified using the ordinary GC-MStechnique to reveal the presence of 19 compounds dominated by dioctyl phthalate. Moreover, the antibacterial activity of the crude oil has been carried out using disk ... continuation of our phytochemical and antibacterial studies of the Algerian Sahara medicinal plants [7-11], we report here the findings of our studies on the composition and anti-microbial activity of ... constituent in visible parts was Dioctyl phthalate (39.84%) and the yield of essential oils was0.9%. These extracts reveal in vitro antibacterial activity on the studied bacterial, confirmed by the inhibition...

Báo cáo y học: "Marked disability and high use of nonsteroidal antiinflammatory drugs associated with knee osteoarthritis in rural China: a cross-sectional population-based survey" ppt

... participated in the concept and design of the study, and the acquisition and interpretation of the data. MF participated in the concept and design of the study, data interpretation, and helped draft the ... manuscript. YKparticipated in the concept and design of the study and data acquisition and interpretation. ZW participated in the concept and design of the study.YZ participated in the concept and ... XKparticipated in the concept and design of the study, data acquisition, and helped draft the manuscript. HL participated in the concept and design of the study, data interpretation, and helped draft the...

Báo cáo y học: "Teaching child and adolescent psychiatry to undergraduate medical students - A survey in German-speaking countries"

... structuralcomponent in the organization of topics to be taught. Alimitation of the present study is the lack of informationon the number of CAP staff and how many studentsthey teach. In the review by Sawyer ... a relatively early stage,with interdisciplinary cooperation just beginning. In Switzerland, child psychiatry is integrated into the psy-chiatry curriculum and thus CAP is required in under-graduate ... E-learning program for medicalstudents; feasibility and evaluation of the acceptance in student training in child and adolescent psychiatry at the University Hospital in Ulm]. ZKinder Jugendpsychiatr...

Báo cáo y học: "Mechanical complications and reconstruction strategies at the site of hip spacer implantation"

... femur and evaluate the effect of a metallic endo-skeleton on the pharmacokinetic properties of the interim prosthesis. Conflict of Interest The authors have declared that no conflict of in- terest ... reports about these complications, only Leunig and colleagues tried to interpret and ex-plain these findings [6]. The authors have recognized that the geometrical form of the spacer plays an im-portant ... Generally, the surgical treatment of these fractures should be planned taking into consideration any further surgical revisions or the later prosthesis reimplantation. If possible, the insertion of...

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