... gap-junctional coupling using flow cytometry.
Methods
Primary lung fibroblast cultures
Primary lines of normal human lung fibroblasts were
established by using an outgrowth from explant following
the method ... ranged from 52 to 61 yr.
Three fibrotic lung fibroblast lines were established from
histologically proven fibrotic lung tissue of 3 patients with
idiopathic...
... regulatory loop by generating knock -in
mouse lines expressing the 75 9Y to F mutation.
Commentary
Altered signalling thresholds in T lymphocytes cause
autoimmune arthritis
Andrew P Cope
Kennedy Institute ... tyrosine
kinase-2 to the receptor complex (for review [4,5]).
Receptor engagement leads to phosphorylation of
tyrosine residues in the cytoplasmic domain of gp130.
Phosphotyrosin...
... horizontal lines in each box indicate median values. Note
that inflammatory indices are higher in SLE patients than in healthy
controls or RA patients and are higher in RA patients than in healthy
controls. ... pro-
inflammatory cytokines and chemokines, causing local tissue
damage and stimulating hypertrophy of smooth muscle cells
in the artery wall. Inflammation is also ex...
... these
proteins, including serum amy loid A (SAA), apolipopro-
tein A-I V (ApoA4), antithro mbin III (synonymous with
SERPINC1), and inter-alpha-trypsin inhibitor heavy chain
H4 (ITIH4; synonymous with inter-alpha-trypsin ... factor-binding protein 4; IHRP:
inter-alpha-trypsin inhibitor family heavy chain-related protein; IPI:
international Protein Index; ITIH4: inter-alpha-trypsin inhibit...
... in SSc patients with
ulcers. Raw intensity signal values present in the sample obtained from
SSc patients with ulcers.
Additional file 3: Modulated genes in circulating endothelial cells of
patients ... expression profile in SSc patients without
ulcers. Raw intensity signal values obtained from the sample of SSc
patients without skin ulcers.
Additional file 5: Genes...
... proinflammatory cytokines were signif-
icantly lower in chronic alcoholic patients than in nonalcoholic
patients in early sepsis is an important new finding. The proin-
flammatory response to invading ... mainly regulated by proinflammatory cytokines [37]. Proin-
flammatory cytokines were significantly decreased in early
septic shock and did not differ in late septic shock. Addi...
... Arendt-Nielsen, Quantitative
posturography in altered sensory conditions: a way to assess balance
instability in patients with chronic whiplash injury. Arch Phys Med Rehabil.
85, 432–438 (2004). doi:10.1016/j.apmr.2003.03.003
24. ... sway exists. As a linear
relationship between pain intensity and COP sway velo-
city has been demonstrated in patients with non-specific
low back...
... pooled from three independent experiments).
Figure 2
Chronic inflammatory infiltrate in B6 mice with collagen-induced arthritisChronic inflammatory infiltrate in B6 mice with collagen-induced ... histological outcome in the two models, hind
paws were fixed, sectioned, and stained with haematoxylin and
eosin. In the early stages of CIA, inflammatory infiltrates were
found in...
... of the hip.
Introduction
Intra-capsular fractures of the femoral neck are extre-
mely common in the elderly population and may be
associated with relatively minor trauma. In the younger
popu ... years after the injury.
Discussion
To ensure efficient t ransfer of power from the rider to
the cycle during cycling, good binding of the feet to the
pedal is beneficial to prevent the foot f...
... acuity was
one in the right eye and 0.6 in the left eye. Our patient
remained asymptomatic at 12-month follow-up, when
visual acuity was one in the right eye and 0.8 in the
left eye.
Discussion
Bilateral ... liver enzymes, serum creatinine,
angiotensin-converting enzyme, erythrocyte sedimenta-
tion rate, vitamin B12, folate and thyroid hormones.
Serum levels of immunoglobulin were 159...