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Báo cáo y học: "Matrix metalloproteinase-8 deficiency increases joint inflammation and bone erosion in the K/BxN serum-transfer arthritis model" pptx

Báo cáo y học:

Báo cáo y học: "Matrix metalloproteinase-8 deficiency increases joint inflammation and bone erosion in the K/BxN serum-transfer arthritis model" pptx

... inflammation and bone erosion in Mmp8-deficient miceTo quantify joint invo lvement, we assessed synovial inflammation and bone erosion in hematoxylin and eosin stained sections of ankle joints, and ... no inflammation; 1 = slight thickening of synovialcell layer and/ or some inflammatory cells in the sublin-ing; 2 = thickening of synovi al li ning and moderate infil-tration o f the sublining; ... tounravel the many ways in which MMP-8 seems to pro-tect against inflammation. Conclusions The present study indicates that MMP-8 protectsagainst inflammatory synovitis and bone erosion in the K/BxN...
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Báo cáo y học: " Protective effect of vasoactive intestinal peptide on bone destruction in the collagen-induced arthritis model of rheumatoid arthritis" pptx

... the enzymes involved in the synthesisof these mediators (cyclooxygenase-2 (COX-2) and inducibleFigure 1Cytokine circulating levels in mice at the end of treatment in the collagen-induced arthritis ... described in this report, VIPtreatment greatly reduces the local expression of both thesecytokines in the joints of arthritic mice, which may account for the block in joint erosion induced in the ... isexpressed by a variety of cell types involved in RA, includingactivated T cells and synoviocytes [8]. These cells, in the pres-ence of cytokines like TNFα and macrophage colony stimulat-ing factor,...
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Báo cáo Y học: Dietary bisphenol A prevents ovarian degeneration and bone loss in female mice lacking the aromatase gene (Cyp19 ) pptx

Báo cáo Y học: Dietary bisphenol A prevents ovarian degeneration and bone loss in female mice lacking the aromatase gene (Cyp19 ) pptx

... xenoestrogens in the ovaries of ArKOmice in vivo.Estrogen plays an important role not only in the reproductive system but also in the regulation of bone metabolism to maintain bone mass. In the present ... (Fig. 6A). In pQCT analysis, the distincttrabecular bone could be detectedvisually, seen as red and yellow, in wild-type mice, but the trabeculae disappeared and the area was occupied by bone marrow, ... markedlyreduced in ArKO mice and the loss of mineralized cancellous bone was evident in the distal metaphysis of the femur in ArKO mice (Fig. 6A). Dietary BPA prevented ArKO micefrom bone loss in...
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Báo cáo y học: "Challenges to conservation: land use change and local participation in the Al Reem Biosphere Reserve, West Qatar" pps

... Park in the USA,arguably the world’s first, was established in 1872, fol-lowed in 1879 by the Royal National Park in Australiasouth of S ydney and the Rocky Mountain National Park in Canada in ... implemented yet and whether there was any functioning system of co-man-agement”. This is exactly the point: there is and thereis not, depending on yo ur viewpoint. Any visitor to the Al Reem ... incorrectly listed in Jemailiya Municipality.7Table2listsQuraAbuRaghedcampinJemailiyaMunicipality, as in the Ministry records.8Data in this and the following table (of March 2009)kindly...
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Báo cáo y học: " Subjective memory complaints, vascular risk factors and psychological distress in the middle-aged: a cross-sectional study" pptx

... considered;thepresenceofobesity,diabetes, whether the personwas a current smoker and whether the individual wascurrently being treated for hypertension or hypercholes-terolaemia. Obesity was defined ... differences in any of the baseline characteristics between the exploratory and confirmato ry samples. Table 3 shows Models 1, 2, 3 and 4 of the multivariate analysis generated with the exploratory sample. ... participation rate of the 45 and Up Study was approximately 18% for the first 100, 000participants [26]. We gained permission from The SaxInstitute to use data from the 45 and Up Study dataset and ethical...
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Báo cáo y học: "Correction: Nitrogen washout/washin, helium dilution and computed tomography in the" pptx

... measured by increasing the FiO2as a function of the EELV obtained decreasing FiO2. The EELV obtained increasing the FiO2was -56 + 1.0078 multiplied by the EELV obtained decreasing the FiO2(r2= ... 0.0001). (b) The Bland-Altman plot of the EELV measurement obtained increasing the FiO2 and the EELV obtained decreasing the FiO2. The x axis shows the mean of the two measurements and the difference ... dilution method. The x axis shows the mean of the two measurements and the y axis shows the difference between the EELV measured by the helium dilution method and the EELV measured by the CT scan...
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Báo cáo y học: "Thrombolysis during out-of-hospital cardiac arrest: a lesson in the law of diminishing returns" pptx

... 3CommentaryIntravascular thrombosis plays a fundamental role in the pathophysiology of cardiac arrest. Autopsy results from cases of unsuccessful resuscitation and coronary angio-graphy in survivors ... underlying acute myocardial infarction or pulmonary embolism. Therefore, thrombolysis during cardiopulmonary resuscitation may improve survival.MethodsObjective: To determine whether thrombolysis ... disseminated intra-vascular coagulation, relatively low fi brinolysis, and a propensity for microcirculatory clot formation [4,5]. Expanded AbstractCitationBöttiger BW, Arntz HR, Chamberlain...
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Báo cáo y học: "Genome-wide investigation reveals pathogen-specific and shared signatures in the response of Caenorhabditis elegans to infection" pot

... endopeptidase activityGO:0004220:cysteine-type peptidase activityKOG1282:lysosomal cathepsin AKOG1543:Cysteine proteinase Cathepsin LGO:0003796:lysozyme activityStress_Down w/ Bt toxin,Cry5B_Huffman2004Stress_Down ... deathKOG1339:aspartyl proteaseInsulin_Down in Dauer_McElwee2004Insulin_Down in daf-2 _McElwee2004Insulin Down in daf-2 Murphy2003Insulin_Up in Dauer_McElwee2004Insulin_Up in daf-2 _McElwee2004Infection_Up ... encodes a protein containing alipopolysaccharide-binding protein (LBP)/bactericidalpermeability-increasing protein (BPI)/cholesteryl estertransfer protein carboxy-terminal domain (Pfam accessionnumber...
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Tài liệu Báo cáo Y học: Granule-bound starch synthase I A major enzyme involved in the biogenesis of B-crystallites in starch granules ppt

Tài liệu Báo cáo Y học: Granule-bound starch synthase I A major enzyme involved in the biogenesis of B-crystallites in starch granules ppt

... enzymes.Detailed in vivo investigationsperformed during the course ofstorage starch synthesis show that amylopectin and amylosesynthesis are partly disconnected and that amylose synthesispersists when the ... amylose continues toaccumulate at the final stage of starch synthesis in the absence of concomitant amylopectin synthesis (reviewed in [41]). In vitrosynthesis of amyloseBecause in Chlamydomonas ... The increase in crystallinity wit-nessed during these first 12 h is in line with the high ratesobserved for amylopectin synthesis. However between 12 and 58 h the rate of amylose synthesis becomes...
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Báo cáo Y học: Guanosine diphosphate-4-keto-6-deoxy-D-mannose reductase in the pathway for the synthesis of GDP-6-deoxy-D-talose in Actinobacillus actinomycetemcomitans potx

Báo cáo Y học: Guanosine diphosphate-4-keto-6-deoxy-D-mannose reductase in the pathway for the synthesis of GDP-6-deoxy-D-talose in Actinobacillus actinomycetemcomitans potx

... hydrolyse them; theywere then dried to remove the water and HCl. The pelletswere converted into the correspondingD-(+)-2-octylglyco-side acetate by the method of Leontein et al. [30]. The ... report on the GDP-6-deoxy-D-talose biosynthetic pathway and the role ofGDP-4-keto-6-deoxy-D-mannose reductase in the synthesisof GDP-6-deoxy-D-talose.Keywords: Actinobacillus actinomycetemcomitans;6-deoxy-talose; ... GDP-4-keto-6-deoxy-D-mannose into GDP-6-deoxy-D-talose in A. actinomycetemcomitans SUNYaB 75 (serotype a), and revealed the enzymatic process involved in GDP-6-deoxy-D-talose synthesis.ACKNOWLEDGEMENTSThis...
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