Báo cáo y học: "Time-dependent changes in pulmonary surfactant function and composition in acute respiratory distress syndrome due to pneumonia or aspiration" pot

... purposes) Respiratory ResearchOpen AccessResearchTime-dependent changes in pulmonary surfactant function and composition in acute respiratory distress syndrome due to pneumonia or aspirationReinhold ... elec-trocardiogram, clinical laboratory tests (hematology, clin-ical chemistry, coagulation), and pulmonary function prior to inclusion into the study.Study design and bronchoscopyIt was predefined that ... comparedwith traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med 2000, 342:1301-1308.15....

Báo cáo y học: "TSLP directly impairs pulmonary Treg function: association with aberrant tolerogenic immunity in asthmatic airway" pps

... effectsof inflammatory cytokine milieu of each disease on pul-monary Treg function might very well be different.Modulation of TSLP signaling has been shown to beinfluential to airway inflammation in ... of Brefeldin A for ELISA.Staining for membrane-bound TGF-b was performedwith standard surface staining protocols. For intracellu-lar cytokine detection, stimulated cells were fixed and permeablized ... signaling pathway resembles that of a cytokinefamily, including IL-2, IL-7, and IL-15, which all acti-vates S TAT5. Surprisingly, unlike TSLP, cytokines suchas IL-2 and IL-15 have been reported...

Báo cáo y học: "Association of functional variants of PTPN22 and tp53 in psoriatic arthritis: a case-control study" docx

... Rheumatoid fac-tor positivity was identified in 9% and 10% of the Newfound-land and Toronto cohorts, respectively. No association wasassociated with rheumatoid factor positivity and the minor ... variant and PsA in theToronto cohort. Because the Toronto cohort is the first popu-lation to report a significant association between PTPN22 and PsA and contradicts previous larger studies in psoriasis ... and theresulting spectra were analyzed and genotypes were deter-mined using the Sequenom SpectroTYPER-RT software. Wegenotyped PsA probands and control individuals for the fol-lowing polymorphisms:...

Báo cáo y học: "Effect of antioxidants on knee cartilage and bone in healthy, middle-aged subjects: a cross-sectional study" ppt

... standard-deviation increase in vitamin C/vitamin E intake before and after adjusting for energy intake, age, gender, and body mass index.dOdds ratio of tibiofemoral bone marrow lesions being present per standard-deviation ... per serving per day increase in fruit/vegetables intake before and after adjusting for energy intake, age, gender, and body mass index.dOdds ratio of tibiofemoral bone marrow lesions being present ... early response of the knee to known risk factors for knee OA [25,26]. For example, changes of bone expansion are seen in response to increased adductormoment [25] and obesity [26] even before changes...

Báo cáo y học: "Diurnal secretion of growth hormone, cortisol, and dehydroepiandrosterone in pre- and perimenopausal women with active rheumatoid arthritis: a pilot case-control study" ppt

... and adrenocorticalabnormalities in a proinflammatory cytokine milieu exacerbatethe inflammatory process and play a role in the pathogenesisof rheumatoid cachexia remains to be determined.Available ... patients with RA, possibly due to reducedcorticotropin-releasing hormone (CRH) activity [8,9].We hypothesized that the excess of systemically releasedinflammatory cytokines characteristic of ... RA [37]. Moreover, our DHEAfindings further suggest that in the setting of heightenedinflammatory and cytokine burden, there is a relative adreno-cortical androgen insufficiency in patients...

Báo cáo y học: " Contrasting chromatin organization of CpG islands and exons in the human genome" pot

... in this way. More elaboratemechanisms involving cis-acting RNA sequences and trans-acting RNA-binding proteins should accompanythis process. Changes in chromatin organization of anexon may ... methylation. CGIs are typicallyunmethylated [25,26], notwithstanding many targetCpGs in them. It is likely that trans-acting regulators areactively recruited to promoter CGIs to maintain thisregion ... was obtained for each bin of all cor-responding exons and introns. ICEs (initial coding exons) and LCEs (last coding exons) are broken into the UTR (light blue or light green) and coding region...

Báo cáo y học: "Uses, traditional management, perception of variation and preferences in ackee (Blighia sapida K.D. Koenig) fruit traits in Benin: implications for domestication and conservatio" pptx

... into water for washing clothes. According to the interviewees, this type of utilization was very pop-ular in the past across the country before the introduc-tion of manufactured soap. Today ... branchesFireprotectionAvoid fire damages to trees that affect fruityield and destroy seedlings and saplingsTillage, weeding and clearing around the seedlings, saplings and treesMulching/organicfertilizationRapid ... traditional agroforestry systems in Benin. Recently , ackee has emerged as high-priorityspecies for domestication in Benin after a national sur-vey and ranking of Non-Timber Forest Products(NTFPs)...

Báo cáo y học: " Functional cooperation of of IL-1b and RGS4 in the brachial plexus avulsion mediated brain reorganizatio" pps

... protein,dynactin, forming binding protein, seri ne peptidase inhi-bitor, tenascin, low density lipoprotein receptor, TRIP -Br1, glia maturation factor, peroxisome proliferatorsactivated receptor. In spinal ... injury istightly controlled by cytokines, G-protein coupled recep-tor pathways [10]. IL-1b and IL-6 in particular, they arenot only implicated in the central inflammatoryresponse in glial cells, ... istocompatibility complex,angiotensin 2, dual-specificity tyrosine kinae, G-proteincoupled receptor 56, FK506 binding protein, N-ras pro-tein, phospholipids D, cytoskeleton associated protein,dynactin,...

Báo cáo y học: " The prevalence of common mental disorders and PTSD in the UK military: using data from a clinical interview-based study" pdf

... weightsb Major depressive syndrome or other depressive syndrome c Panic syndrome or other anxiety syndrome d Any depressive syndrome, any anxiety syndrome or somatisation disorderBioMed ... for those who leave the Armed Forces [2,3].Many factors, including deployment and combat, areknown to increase the risk of psychological distress and psychiatric injury [4,5]. Recent US reports ... unexplained symptoms after theTable 3: Associations of PTSD symptoms with status and deployment history, odds ratio (OR) a and 95% confidence intervals (CI)PTSD symptomsVariable Unadjusted OR...

Báo cáo y học: " Comparison of the efficacy of lamivudine and telbivudine in the treatment of chronic hepatitis B: a systematic review" pdf

... final manuscript.Competing interestsThe funding source had no influence on study design, in the collection,analysis, and interpretation of the data, in the writing of the manuscript, or in ... clearly needed to guide evolving standards of carefor CHB.AcknowledgementsThis work was financial supported by the Innovative Experimental Programfor Undergraduates (YA09057).Author details1Department ... Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ,McQuay HJ: Assessing the quality of reports of randomized clinical trials:is blinding necessary? Control Clin Trials 1996,...

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