... 2001
Economic Aspects of Disease Monitoring with Special
Reference to Bovine Paratuberculosis
By Larry G. Paisley
National Veterinary Institute, Norway. Present address: Danish Veterinary Laboratory, ... of approxi-
mately 5%. However, the herd-level specificity
would be approximately 99.7%
Another way to decrease the expected number
of false positive reactors would be...
... degrees of stress
to a highly-embedded sentence. The second is
to reaxrange the boundaries given by the syn-
tax when the intonational phrasing of an utter-
ance does not correspond to its ...
allowed to vary from language to language.
It is possible, however, to postulate the ex-
istence of a large, fixed, language-universal
set of phonological features and a fixed...
...
ity with
WITH 1)
WITH 8: with * to
talk with pilots
friendly with Latin American countries
WITH 9: with *
filled with milk
filled with bad odors
Compare this with
OF 13.
WITH 10: with ...
TO 1: to *——
farthest to the right
path to one side
lands to the east
far to the north
TO 2: to * (motion) towards
come to the edge
went to them...
... Ministry of Education,
Culture, Sports, Science, and Technology of Japan to
H. Sakurai.
References
1 Fujimoto M & Nakai A (2010) The heat shock factor
family and adaptation to proteotoxic stress. ... repression of mouse heat shock factor 1.
Mol Cell Biol 18, 906–918.
13 Newton EM, Knauf U, Green M & Kingston RE
(1996) The regulatory domain of human heat shock
factor 1 is s...
... feature of chemokines is the redundancy
of the system. Several chemokines bind to more than
one receptor, and the majority of chemokine receptors
have multiple ligands, leading to the generation of
multiple ... 3¢-untranslated
region of the SDF-1 gene is associated with the annual
rates of radiographic progression, but not with suscep-
tibility to RA. However, the functi...
... (Institute Of Rheumatology, Rheu-
matoid Arthritis)]. We concluded that RA disease activ-
ity tends to be negatively associated with the presence of
JCP and speculated that patients with JCP have ... chronic
inflammatory disease that affects 0.5–1% of the popu-
lation and causes progressive joint destruction that
leads to the restriction of activities of daily living and...
... FEBS
MINIREVIEW
Molecular aspects of rheumatoid arthritis: role of
transcription factors
Hiroshi Okamoto
1
, Thomas P. Cujec
2
, Hisashi Yamanaka
1
and Naoyuki Kamatani
1
1 Institute of Rheumatology, Tokyo Women’s ... proliferator-activated
receptors (PPARs) are such examples. Peroxisome
proliferator-activated receptors are members of the
nuclear hormone receptor family, the largest...
... galactokinase in order to see which mechanistic
class it falls into (Fig. 4). a-
D
-Galactose 1-phosphate was
found to be an uncompetitive inhibitor with respect to
galactose (K
IU
¼ 28 ± 11 m
M
) ... the catabolism of galactose. The sugar is phosphor-
ylated at position 1 at the expense of ATP. Lack of fully
functional galactokinase is one cause of the inherited disease
gal...
... fragments of the K
+
-channel (c) insertion of
CaM between two domains of the anthrax exotoxin (d)
binding of Ca
2+
ions to only one EF-hand pair and (e)
binding of CaM in an extended conformation to ... cyclase exotoxin
The crystal structures of the C-terminal fragment (residues
291–800) of the exotoxin from Bacillus anthracis,withand
without its activator calmodulin, is th...
... changes to the volume of the
side-chain that are likely to disrupt the local fold.
These two residues, together with N34, are located
within 0.15 nm of each other and all are at, or close
to, the ... of UDP-galactose to UDP-glucose was cou-
pled to the oxidation of UDP-glucose using the enzyme
UDP-glucose dehydrogenase (Sigma; EC 1.1.1.22). This
results in the reduction of...