Báo cáo y học: "Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice" docx
Báo cáo y học: "Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice" docx
... detect-able cytokines and chemokines, such as IL-12, keratino-cyte-derived cytokine, IFNγ-induced protein, and macrophage inflammatory protein-1α, were not indepen-dently associated with changes in diet, ... distribution, and reproduction in any medium, provided the original work is properly cited.Research articleDiet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors ... Intra-assay and inter-assay coefficients of variation for IL-1α were 4.2% and 4.5%, respectively, and for IL-1-receptor antagonist were2.4% and 5.7%, respectively.The following cytokines and...
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Báo cáo y học: "Texture analysis of cartilage T2 maps: individuals with risk factors for OA have higher and more heterogeneous knee cartilage MR T2 compared to normal controls - data from the osteoarthritis initiative" pptx
... 77.1 kg) knee injury (defined as a history of knee injury causing difficultly walking for at least one week), knee surgery(defined as a history of knee surgery, including meniscal and 8. Li ... study: baseline clinical dataset 0.2.2, baseline imaging datasets 0.E.1 and 0.C.2. The Institutional Review Boards at all units participating in the Osteoarthritis Initiative, including the clinical ... centers and the OAI Coordinating Center at UCSF, have reviewed and approved the protocol and consent forms for the Osteoarthritis Initiative study. All OAI study participants sign informed consent...
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Báo cáo y học: "Lack of association between glucocorticoid use and presence of the metabolic syndrome in patients with rheumatoid arthritis: a cross-sectional study" ppsx
... factors may contribute to the increased cardiovascular risk, including classical risk factors such as smoking, diabetes,hypertension, and obesity and novel risk factors such as sys-temic inflammation, ... morbidity and mortality, attributed toboth traditional and novel cardiovascular risk factors. Themetabolic syndrome, a cluster of classical cardiovascular risk factors, including hypertension, obesity, ... metabolic syndromemay already be extensively modified by other processes in RA(including chronic inflammation and treatments other than GCs),leaving little scope for additive effects of GCs.IntroductionAn...
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Báo cáo y học: "Lack of association between glucocorticoid use and presence of the metabolic syndrome in patients with rheumatoid arthritis: a cross-sectional study" pptx
... factors may contribute to the increased cardiovascular risk, including classical risk factors such as smoking, diabetes,hypertension, and obesity and novel risk factors such as sys-temic inflammation, ... morbidity and mortality, attributed toboth traditional and novel cardiovascular risk factors. Themetabolic syndrome, a cluster of classical cardiovascular risk factors, including hypertension, obesity, ... metabolic syndromemay already be extensively modified by other processes in RA(including chronic inflammation and treatments other than GCs),leaving little scope for additive effects of GCs.IntroductionAn...
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Báo cáo y học: "proving draft assemblies by iterative mapping and assembly of short reads to eliminate gaps" docx
... estab-lishes new linkage information between the newlysequenced reads and any existing assembly by mapping, and then improves the assembly by localised assembly ofreads at real gaps and regions that ... main stages: aligning sequencereads against an initial assembly to identify those that canbe used for gap-spanning; and local assembly of theselected subset of reads and updating of the initial ... assem-bly by inserting newly assembled contigs to walk intogaps. The two stages can be run repeatedly, producing animproved assembly at each stage for use in the next itera-Figure 4 Closing gaps in...
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Báo cáo y học: " Intermittent long-wavelength red light increases the period of daily locomotor activity in mice" ppsx
... locomotor activityActivity events were grouped into 5-minute bins by theStanford Chronobiology Systems' (Stanford, CA) dataprocessing and automatic storage system integrated into aDell computer. ... nmonly. Care in the darkroom consisted of ten min per day and each mouse was inspected for less than a minute.Daily visits occurred at random times between 8 am and 5 pm.Locomotor activity assessmentDaily ... drop sharply and is vanishingly small at wavelengthsabove 600 nm (orange light) [7-9]. In mice lacking rods and cones, the peak sensitivity for phase-shifting is 481nm, and sensitivity drops to...
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Báo cáo y học: "Logistic Organ Dysfunction Score (LODS): A reliable postoperative risk management score also in cardiac surgical patients" pps
... al: Risk factors for multiple organ system failure and death in critically injured patients. Surgery 1993, 114(1):21-30.23. Hebert PC, et al: A simple multiple system organ failure scoring systempredicts ... study populationSurgery number %CABG 1526 54.5Isolated valve surgery 635 22.7Combined CABG and valve surgery 381 13.6Ascending aorta and aortic arch surgery 60 2.1Combined ascending aorta and ... reliable in predicting mortality in the whole study group (institutional or national regis-try level). On the other hand, good discriminationmeans that thi s score is useful in predicting mortalityon...
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Báo cáo y học: " Open Access The association between bullying and early stages of suicidal ideation in late adolescents in Greece" pdf
... thathelped in the interpretation of the results. VM helped in obtaining funding for the study, in the writing of the paper and interpretation of the results.All authors read and approved the final ... rela-tionship whereby an increase in the intensity (either fre-quency or severity) of bullying would lead to greaterreporting of suicidal ideation. One study that examinedthis issue failed to find c onsistently ... of Psychiatric MorbidityPsychiatric symptoms were assessed with the revisedclinical interview schedule (CIS-R), a fully structuredpsychiatric interview designed to be used by trained layinterviewers...
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Báo cáo y học: " Initiation of bacteriophage T4 DNA replication and replication fork dynamics: a review in the Virology Journal series on bacteriophage T4 and its relatives" pptx
... are coated by the single-strand binding pro-tein gp32, UvsY acts as a mediator protein in loadingUvsX onto gp32-coated ssDNA, and UvsX is the strand-invasion protein (RecA and Rad51 homolog). ... terminallyredundant, or it may be within the interior region of aco-infecting T4 DNA mol ecule, since T4 DNA is alsocircularly permuted. In this way, the process of RDR can in principle initiate ... displaced strandof the D-loop allows lagging strand synthesis (panel A). In bubble-migration synthesis, lagging strand synthesis does not occur, and the newlysynthesized single strand is extruded...
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Báo cáo y học: "Circulating surfactant protein -D is low and correlates negatively with systemic inflammation in early, untreated rheumatoid arthritis" pps
... betweenSP-D and the Met11Thr polymorphism in early,untreated RA, and by studying the correlation betweenSP-D and disease activity measures and radiographicprogression during a four-year interventional ... x-ray findings and SP-D. SP-D was quantified by enzyme-linkedimmunosorbent assay (ELISA) and molecular size distribution was assessed by gel filtration chromatography.Further, SP-D Met11Thr single ... MAPK[48]. Inflammatory signalling resulting in p38 phosphory-lation has been identified as an important determinant ofsynovitis severity [49]. Thus, in theory the dominance oflow molecular...
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