... article as: Pfarr et al.: Hemodynamic and clinical onset in
patients with hereditary pulmonary arterial hypertension and BMPR2
mutations. Respiratory Research 2011 12:99.
Submit your next manuscript ... testing may become
of increasing clinical relevance. Patients with BMPR2
mutation t end to a more severe clinical phenotype and
might be followed more clo...
... issues
jointly; that is, to investigate plasma homocysteine levels
in patients with MS and depression.
Accordingly, the present study was designed in order to
assess Hcy plasma levels in MS patients and ... Hcy
increases were observed in MS patients with vitamin B12
deficiency [7,18,19]. Our results, in agreement with
Vrethem et al. [8] and Ramsaransing et al. [9],...
... resulted in clini-
cal and symptom i mprovement within 4 weeks of treat-
ment initiation with significant increases in remission
rates and patient functioning. RLAI also was found to be
effective in ... psychiatric intervention in the pre-
vious 12 months [15]. In the or iginal study, subjects
with any degree of mood symptom severity were
included. T he current analysis focu...
... abnormal
responses to insulin and diabetes-like glucose tolerance
curves [8,9] were observed in psychiatric patients. Pla-
nansky and Heilizer [10] reported weight gain already in
1959 in patients treated with ... that
changes in metabolic parameters in patients treated with
antipsychotics may, in part, be genetically determined
[17].
MetS is characterized by the coin...
... that withdrawing
ICS results in an increase in the likelihood of an exacer-
bation but from WISP there is no indication that doing
so in a routine clinical setting with patients participating
Favours ... the
definition of outcome and setting and management of
patients within the trial. Clarity is needed in the report-
ing of these trials, particul arly in defining exacer...
... alkanes and methylated alkanes
have proved to be highly discriminating in distinguishing
lung cancer patients from healthy controls, but breath
analyses can be affected by both clinical and analytical
confounding ... compounds into three groups (table 4) and
suggests some fascinating hypoteses. It may be particu-
larly relevant in distinguishing substances of endogenous
Classifi...
... YG, Christen WG, Foster SC: Correlation of metal-
loproteinase-2 and -9 with proinflammatory cytokines inter-
leukin-1β, interleukin-12 and the interleukin-1 receptor
antagonist in patients with ... expression of
a 92-kD gelatinase (type V collagenase) by rheumatoid syno-
vial fibroblasts and its induction in normal human fibroblasts
by inflammatory cytokines. J Clin Invest 19...
... lymphocytes of patients with com-
mon variable immunodeficiency (CVI) produce reduced levels
of interleukin-4, interleukin-2 and interferon-gamma, but pro-
liferate normally upon activation by ... immuno-
deficiency: clinical and immunological features of 248
patients. Clin Immunol 1999, 92:34-48.
2. Levy Y, Gupta N, Le Deist F, Garcia C, Fischer A, Weill JC, Rey-
naud CA: Defect...
... non-tissue-damag-
ing painful stimulation in healthy adults [15,16], patients with
juvenile RA [17], and patients with persisting low back pain
[18].
Given that RA patients experience persistent pain and chronic
inflammation, ... at
several time points: immediately after testing and 15, 30, and
60 minutes after testing.
Psychophysical pain testing (45-minute session)
Mecha...
... these
data be interpreted cautiously and not be overly general-
ized. Initiation of RLAT at the beginning of the study was
the only clinical mandate, and treatments for schizophre-
nia including additional ... although the
incidence of extrapyramidal AEs may vary among the
atypical antipsychotics [13]. Atypical long-acting antipsy-
chotic therapy, a relatively new treatment modality in...