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Báo cáo y học: " Efficacy and safety of once-daily aclidinium in chronic obstructive pulmonary disease" potx

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Báo cáo y học: " One-year treatment with mometasone furoate in chronic obstructive pulmonary disease" docx

... Synarc,Inc. (Portland, OR).The efficacy and safety analyses were based on allrandomized subjects (intent-to-treat population). Aconfirmatory analysis of subjects who met key eligibility and evaluability ... 80%adherence in recording diary data between screening and baseline.Study designThis was a randomized double-blind, placebo-con-trolled, parallel-group study in males and females of any race, ≥ 40 years ... S, Peterson S and Olsson H: Efficacy and safety of budesonide/formoterol in the management of chronic obstructive pulmonary disease. Eur Respir J 2003, 21(1):74–81.33. Calverley PM, Spencer...
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Báo cáo y học: "Efficacy and safety of aripiprazole in the treatment of bipolar disorder: a systematic review" pdf

... (dehydro-genation, hydroxylation, and N-dealkylation), mainly bycytochrome P450 2D6 (CYP2D6) and cytochrome P4503A4 (CYP3A4) [60]. The parenteral drug is excreted only in traces. There is only ... Pharmacokinetics and tolerability of intra-muscular, oral and intravenous aripiprazole in healthysubjects and in patients with schizophrenia. Clin Pharmacokinet2008, 47:475-485.64. Findling RL, ... in acute mania and in the maintenance treatment of bipolardisorder, with a favourable safety and tolerability profile,with minimal propensity for clinically significant weightgain and metabolic...
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Báo cáo y học: " Efficacy and safety of an antiviral Iota-Carrageenan nasal spray: a randomized, double-blind, placebo-controlled exploratory study in volunteers with early symptoms of the common cold" doc

... current smoking, rela-tionship to any study personnel, and administration of any investigational drug or participation in any otherclinical trial within 4 weeks of entry into our study. Allco-existent ... Eccles et al.: Efficacy and safety of an antiviral Iota-Carrageenan nasal spray: a randomized, double-blind, placebo-controlled exploratory study in volunteers with early symptoms of thecommon ... spray (black squares) and Placebo (black triangles) treatment groups. The y axis shows the day of recording. The y axis shows the study day; i indicates the point of inclusion into the study.Eccles...
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Báo cáo y học:

Báo cáo y học: " Efficacy and safety of once-daily aclidinium in chronic obstructive pulmonary disease" potx

... Efficacy and safety of once-daily aclidinium in chronic obstructive pulmonary disease. Respiratory Research2011 12:55.Submit your next manuscript to BioMed Central and take full advantage of: ... Lamarca R, Garcia GE, Ferrer P: Safety and pharmacokinetics of single doses of aclidinium bromide, a novel long-acting, inhaledantimuscarinic, in healthy subjects. Int J Clin Pharmacol Ther 2009,47:460-468.7. ... airway narrowing in chronic obstructive pulmonary disease (COPD); therefore, inhaled anticholiner gic agentsplay a key role in the treatment of this disorder [1]. TheGlobal Initiative for Chronic...
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Báo cáo y học: "Efficacy and safety of tiotropium in COPD patients in primary care – the SPiRiva Usual CarE (SPRUCE) study" ppsx

... Committee of the BTS.Thorax 1997, 52(suppl 5):S1-S28.2. Chronic Obstructive Pulmonary Disease: Management of Chronic Obstructive Pulmonary Disease in Adults in Primary and Secondary Care. NICE Clinical ... Boehringer Ingelheim and Pfizer.References1. British Thoracic Society: BTS guidelines for the management of chronic obstructive pulmonary disease. The COPD Guide-lines Group of the Standards of ... Secondary endpoints included: trough forced vital capacity (FVC)response, weekly use of rescue short-acting β-agonist, and exacerbation of COPD (complex of respiratory symptoms/events of >3 days...
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Báo cáo y học: "Efficacy and safety of non-invasive ventilation in the treatment of acute cardiogenic pulmonary edema – a systematic review and meta-analysis" docx

... Antonelli4 and Jeremy C Wyatt51Department of Pulmonology, Faculty of Medicine, University of Porto, Portugal2Department of Biostatistics and Medical Informatics, Faculty of Medicine, University of ... to understand.The aim of our study was to systematically review the evidence in order to answer key clinical questions about the efficacy and safety of CPAP and NPPV in the treatment of patients ... purposes)Vol 10 No 2Research Efficacy and safety of non-invasive ventilation in the treatment of acute cardiogenic pulmonary edema – a systematic review and meta-analysisJoão C Winck1, Luís F Azevedo2,3,...
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Báo cáo y học: "Effectiveness and safety of adalimumab in patients with ankylosing spondylitis or psoriatic arthritis and history of anti-tumor necrosis factor therapy" pdf

... College of Rheumatology; AS: ankylosing spondylitis; ASAS:Assessment of SpondyloArthritis International Society; BASDAI: Bath Ankylos-ing Spondylitis Disease Activity Index; BASFI: Bath Ankylosing ... Ankylosing SpOnDYlitis(RHAPSODY) and SafeTy and Efficacy of Adalimumab in Patients with Active Psoriatic Arthritis (PsA): An Open-Label, Multinational Study to Evaluate the Response toEvery-Other-Week ... effectiveness and safety of adalimumab in treating patients with active ASor PsA who had a history of therapy with IFX or ETN orboth: Review of Safety and Effectiveness witH Adali-mumab in Patients...
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Báo cáo khoa học: "Efficacy and safety of a low-flow veno-venous carbon dioxide removal device: results of an experimental study in adult sheep" pps

... over-distension and cyclic inflation and deflation of alveoli can damage the alveolar–capillary barrier and initiate oramplify a local and systemic inflammation, so the concept of ventilator-induced lung injury ... (Modena), Italy) and treatment was started. Nochanges in ventilatory setting were made during the treatment.A bolus of 2,000 UI of heparin was administered intravenously,followed by an infusion ... pressure Pulmonary artery wedge pressure Pulmonary artery pressureSystemic and pulmonary vascular resistanceClinical parameters DiuresisBody temperatureFluid balanceVentilator setting FiO2Tidal...
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Báo cáo y học: "Utility and safety of draining pleural effusions in mechanically ventilated patients: a systematic review and meta-analysis" pps

... (asdefined in each study), and the remaining 3 % had inde-terminate biochemical findings.Methodological qualityThere were no randomized or non-randomized con-trolled trials of effusion drainage. ... 14 of 14Table 1 Summary of studies included in the systematic review (Continued)Ahmed2004 [33]Measure effects of thoracentesis onhemodynamic and pulmonary physiologySingle-centreprospectivecohortMechanically ... including the use of imaging guidance, the level of training of the operator, and the type of drainage proce-dure performed; and outcomes. Only outcomes reported in mechanically ventilated patients...
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Báo cáo Y học: Phosphorylation and dephosphorylation of histidine residues in proteins Susanne Klumpp and Josef Krieglstein Abteilung Biochemie und Institut fu¨r Pharmakologie und ppt

Báo cáo Y học: Phosphorylation and dephosphorylation of histidine residues in proteins Susanne Klumpp and Josef Krieglstein Abteilung Biochemie und Institut fu¨r Pharmakologie und ppt

... histidine. The serine/threonineprotein phosphatases type 1, t ype 2 A a nd type 2C, in contrast, a re highly active against phosphohistidine in histone H4 (reviewed in [1]). Intriguingly, none of ... appearance and disappearance of phos-phohistidine on P-selectin are very rapid.The next finding of an intracellular signaling systeminvolving histidine phosphorylation in mammals appeared in 2000 ... 1071 In addition to well known phosphorylation on serine,threonine and tyrosine residues, thrombin and collagen leadto the phosphorylation of histidine in the cytoplasmic tail of P-selectin....
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