Báo cáo y học: "Regulation of IFN response gene activity during infliximab treatment in rheumatoid arthritis is associated with clinical response to treatment" potx
Báo cáo y học: "Regulation of IFN response gene activity during infliximab treatment in rheumatoid arthritis is associated with clinical response to treatment" potx
... the original work is properly cited.Research articleRegulation of IFN response gene activity during infliximab treatment in rheumatoid arthritis is associated with clinical response to treatment Lisa ... disease during IFN /β treatment and circulating IFN inducers [2,3].Type I IFN activity in SLE is associated with diseaseseverity [1]. TNF was the first cytokine convincinglydemonstrated to ... poor response to infliximab treatment is associated with treatment- induced increase in type I IFN response gene activity. Discussion In this study, we demonstrated that blockade of theinflammatory...
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Báo cáo y học: "Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis" pptx
... CC, Lin YL, Huang JL: Associationbetween serum inflammatory cytokines and disease activity in juvenile idiopathic arthritis. Clin Rheumatol 2002, 21:52-56.37. Maini RN, Feldman M: How does infliximab ... major proinflammatory cytokines in RAjoints and stimulate IL-6 production by synovial fibroblasts [33-37], whereas IL-6 is a major circulating cytokine in RA thatinduces the acute phase response, ... patients with cor-onary artery disease the coronary plaques and adventitia con-tained large numbers of B cells, whereas in coronary arterydisease it is typical for lymphocytic infiltrates to consist...
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Báo cáo y học: "Validation of the reshaped shared epitope HLA-DRB1 classification in rheumatoid arthritis" pptx
... susceptibility to rheumatoid arthritis. Arthritis Rheum 1987, 30:1205-1213.2. Meyer JM, Han J, Singh R, Moxley G: Sex influences on the pen-etrance of HLA shared-epitope genotypes for rheumatoid arthritis. ... Lasbleiz S, Bardin T, Prum B, Cornélis F: Rheumatoid arthritis seropositive for the rheumatoid factor is linked to the proteintyrosine phosphatase nonreceptor 22–620 W allele. Arthritis Res Ther ... evaluating the relative effects of polymorphismswithin a gene using case/control or family data: application to HLA in type 1 diabetes. Am J Hum Genet 2002, 70:124-141.12. Stata software by Clayton...
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Báo cáo y học: "Development of a health care utilisation data-based index for rheumatoid arthritis severity: a preliminary study" ppt
... validity of a rheumatoid arthritis medical records-based index of severity compared with the DAS28. Arthritis Res Ther 2006, 8:R57.18. Deyo RA, Cherkin DC, Ciol MA: Adapting a clinical comorbidityindex ... review study period. The variables for rheuma-tology visits, inflammatory markers and other laboratory mark-ers yielded the highest correlation with the RARBIS. In ouranalysis using administrative ... rheumatoid arthritis severity (CIRAS) score (mean, range) and Spearman correlation of CIRAS score with rheumatoid arthritis records-based index of severity (RARBIS)RARBIS with medication RARBIS without...
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Báo cáo y học: "Effect of a short-term HAART on SIV load in macaque tissues is dependent on time of initiation and antiviral diffusion" pot
... quantification of total SIV DNA, SIV 2 LTR circles and SIV RNA in tissue were performed as previously described [3]. In situ hybridisationSIV gag in situ hybridization combined with immunohis-tochemistry ... HAART initiated very early during acute infection on HIV reservoirs remains poorly documented, particularly in tissue kno wn to activelyreplicate the virus. In this context, we used the model of ... viremia peak, the effect of treatment wasstrongerinthegutthaninthesecondarylym-phoid tissues; this is likely due to the very heteroge-neous tissue diffu sion of several of the antiret roviraldrugs.ResultsA...
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Báo cáo y học: " Performance of the international physical activity questionnaire (short form) in subgroups of the Hong Kong chinese population" doc
... 0.14***ActiGraph-min: time spent in moderate -to- vigorous physical activity (2 × minutes spent in vigorous activity + minutes spent in moderate-intensity activity, ActiGraph-count: raw counts in hours with any ... lifting activities.This raises the possibility that the accuracy of theIPAQ-C may be improved by separating physical activity into occupational and leisure types (as in the GlobalPhysical Activity ... onreducing the IPAQ-ActiGraph correlation in this study. In practice, physical activity measurements may bemost relevant in grouping participants into differentintensity levels of physical activity...
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Tài liệu Báo cáo khoa học: Stimulation of poly(A) synthesis by Escherichia coli poly(A)polymerase I is correlated with Hfq binding to poly(A) tails ppt
... series of gel-shiftexperiments in order to generate a hierarchy of Hfqbinding efficiency to these different RNAs harboringinternal or 3¢ terminal presumptive binding sites.Interestingly, Fig. ... stimulates ompA mRNAdecay by interfering with ribosomes binding. Genes Dev14, 1109–1118.11 Moll I, Afonyushkin T, Vytvytska O, Kaberdin VR &Blasi U (2003) Coincident Hfq binding and RNase Ecleavage ... FEBSATPase activity and to affect polyadenylation of bac-terial RNAs [25–27].Polyadenylation is ubiquitous in all organisms buthas opposite effects on mRNA stability in prokaryotesand eukaryotes....
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Báo cáo y học: " Regulation of cardiac microRNAs by serum response factor" potx
... actin CArG-binding factor is indistinguishable from the c-fos serum response factor.Mol Cell Biol 1989, 9(2):515-522.9. Miano JM: Serum response factor: toggling between disparate programs of ... participated in the coordination of the study and the writing of the manuscript. SH participated in bioinformatics analysis. JYW led the study and participated in the design of the study, the statistical ... are down-regu-lated in cardiac hypertrophy and cardiac failure, suggest-ing that they may play a role in the underlyingpathogenesis [14,43]. It is plausible that increasing mir-1and mir-133a...
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Tài liệu Báo cáo Y học: Regulation of transcription of the Dnmt1 gene by Sp1 and Sp3 zinc finger proteins doc
... University of Tokyo, JapanThe Sp family is a family of transcription factors thatbind to cis-elements in the promoter regions of variousgenes. Regulation of transcription by Sp proteins is basedon ... the activity of p300 is dependent on gene dosage during earlyembryogenesis. Thus, it is possible that Sp3 might competefor binding to DNA with Sp1-like proteins and Kru¨ppel-like factors ... these factors is independentlyregulated by different coactivators in a cell-cycle-dependentmanner. The distinct functions of Sp1 and Sp3 in theregulation of expression of the Dnmt1geneduringthecellcycle...
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Báo cáo Y học: Regulation of a1,3galactosyltransferase expression in pig endothelial cells Implications for xenotransplantation doc
... promoter is independent of TATA-binding-protein -associated factors and initiator-bindingproteins. Mol. Cell Biol. 17, 2973–2984.32. Weis, L. & Reinberg, D. (1992) Transcription by RNA poly-merase ... necrosis factora-activation of P EC-A cells. However, the magnitude of thischange induced by in ammatory conditions could beinsufficient to affect cell surface a1,3-galactosylation.Keywords: ... J.,Cummings,R.D.&Lowe,J.B.(1989)IsolationofacDNAencoding a murine UDPgalactose: beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide alpha-1,3-galactosyltransferase: expression clon-ingbygenetransfer.Proc....
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