Báo cáo khoa học: "Deletions of neuraminidase and resistance to oseltamivir may be a consequence of restricted receptor specificity in recent H3N2 influenza viruses" doc

... loss of NA, and the ability of the human H3N2 viruses to grow in the presence of an NA inhibitor, is not accom-panied by changes in HA and appears to be a new mecha-nism of resistance to NA inhibitors; ... Hemagglutinin specificity and neuraminidase coding capacity of neuraminidase- deficient influenza viruses. Virology 1997, 229:155-165.24. Bantia S, Ghate AA, Ananth SL, Babu YS, Air GM, Walsh ... similar specificity of HA and NA, and there areseveral reports describing reciprocal changes in HA affin-ity and NA activity [3-5]. However, the specificities of HA and NA are not always matched...

báo cáo khoa học: "Trichoderma viride cellulase induces resistance to the antibiotic pore-forming peptide alamethicin associated with changes in the plasma membrane lipid composition of tobacco BY-2 cells" potx

... the inability of xylanase to elicit ala-methicin resistance. If alamethicin resistance were part of a generalresponse to pathogen attack it would be reasonable to assume that many common plant ... state d, a concentration of 20 µg ml-1 of alamethicin was used. Resistance against permeabilisati on was determined asthe ratio between the s lope 10 min after alamethicinaddition and the initial ... the induction of alamethicin resistance (Additional file 2). None of the elicitorsexamined gave an alamethicin resistanc e in the vicinity of that attained after CM treatment (Figure 4). In addi-tion,...

Báo cáo khoa học: Saccharomyces cerevisiae Ybr004c and its human homologue are required for addition of the second mannose during glycosylphosphatidylinositol precursor assembly ppt

... yeast GPIs [9] and of certain humanGPIs [10–12], and additional side-branching phospho-ethanolamines (EthN-Ps) may be added to the ﬁrst and second mannoses of yeast [13–15] and mammalianGPIs [16,17].S. ... defects are a block in the incorporation of [3H]inositol into protein, consistent with abolition of GPI anchoring, and the accumulation of a PI-PLC-resistant, base-labile [3H]inositol-labeled ... 3115–3128.6 Kawagoe K, Kitamura D, Okabe M, Taniuchi I, IkawaM, Watanabe T, Kinoshita T & Takeda J (1996) Glyco-sylphosphatidylinositol-anchor-deﬁcient mice: implica-tions for clonal dominance of...

Báo cáo khoa học nông nghiệp " Selection and development sweet potato varieties with high root quality for food processing in Northern and Central of Vietnam " MS4 pot

... Center of Weather Forecast in Quang Tri province 4.4. Evaluate and and select new potato varieties in Bac Giang and Thanh Hoa In Bac Giang and Thanh Hoa, mean weight of roots harvested was determined ... sweet potato growth in three provinces of Bac Giang, Thanh Hoa and Quang Tri in 2008-2009 - Evaluate and and select new potato varieties in Bac Giang based on quality and yield - Evaluate and select ... super as well as 30% of Urea and 30% of Kali for treament before planting. - Half of the remaining Urea and Kali lefts was fertilized 20-25 days after planting. The other half was added in 40 to...

báo cáo khoa học: " Knowledge transfer & exchange through social networks: building foundations for a community of practice within tobacco control" potx

... translate into a large population health effect. Tobacco control is a lead-ing area of behavioural eHealth research [15,21-24] in spite of the challenges in applying standard research mod-els to ... including funding representativesfrom the National Cancer Institute in the US and HealthCanada. The 2005 meeting served as a follow-up to an ini-tial, smaller meeting held in Toronto in January ... thinking in that it encouragesself-organization and is suited a transorganizational struc-ture that lacks a centralized command. The CoP approach to KTE has garnered attention within tobacco...

báo cáo khoa học: " Institutionalizing evidence-based practice: an organizational case study using a model of strategic change" pdf

... don't hit that targetagain and again and again, what does that mean' (formalleader two).Finally, there was a predominance of task-based nursingas opposed to knowledge orientation: ... note, and document data had yet to be ade-quately operationalized and thus realized as a routine,day -to- day activity. It is also of note that the two top lead-ers at the beginner site, comparable ... patient and myself and, again, that vis-ibility and someone who is approachable every day and not that the people that are in place aren't helpful, it'sagain, probably having enough availability...

báo cáo khoa học: " The BARRIERS scale -- the barriers to research utilization scale: A systematic review" ppt

... discouraging [1-12]. Despite efforts to increase research use, translating research findings into clinical practice and ensuring they are implemented and sustained remains a challenge. A strategy ... BARRIERS scale to assess clini-cians', administrators', and academicians' perceptions of barriers to the use of research findings in practice [16]. Respondents are asked to rate the ... Bay, Ontario P7B 5E1, Canada and 5School of Nursing, Deakin University and Cabrini-Deakin Centre for Nursing Research, Cabrini Institute, 183 Wattletree Road Malvern 3144, Victoria, AustraliaReferences1....

Tài liệu Báo cáo khoa học: The Arabidopsis protein kinase Pto-interacting 1-4 is a common target of the oxidative signal-inducible 1 and mitogen-activated protein kinases docx

... usingthe following primers: ACT2 (At3g18780): 5-ACATTGTGCTCAGTGGTGGA-3 and 5-CTGAGGGAAGCAAGAATGGA-3, OXI1 (At3g25250): 5-GACGAGATTATCAGATTTTACGC-3 and 5-AACTGGTGAAGCGGAAGAGAC-3, PTI1-4 (At2g47060): ... 1425.39 Matsuoka D, Nanmori T, Sato K, Fukami Y, KikkawaU & Yasuda T (2002) Activation of AtMEK1, an Ara-bidopsis mitogen-activated protein kinase kinase, in vitro and in vivo: analysis of active ... used as an artiﬁ-cial substrate to assess the kinase activity and GST alone wasused as a negative control. The top panel shows the kinase assayvisualized by autoradiography and the bottom panel...

Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx

... increase in malonyl-CoA promotes a decrease in neuropeptide Y and agouti related peptide in hypo-thalamic malonyl-CoA while promoting an increase in proopiomelanocortin and cocaine and amphetamineregulated ... CPT1c to mediatechanges in feeding behavior and body weight. ACC, acetyl-CoA car-boxylase; AMPK, 5¢ AMP kinase; CPT, carnitine palmitoyltransfer-ase; FAS, fatty acid synthase; MCD, malonyl-CoA ... metabolicintermediates in fatty acid biogenesis, including malonyl-CoA and long-chain acyl-CoAs, have been implicated as signaling mediators in the centralcontrol of body weight. Malonyl-CoA has been...

Tài liệu Báo cáo khoa học: X-ray crystallographic and NMR studies of pantothenate synthetase provide insights into the mechanism of homotropic inhibition by pantoate docx

... hydrogen-bonded to the O1 atom of pantoate in site I. The O4 atom of pantoate in site II and theO1 atom of pantoate in site I are hydrogen-bonded via a water molecule. Structural stabilization of ligands ... 164° and )169° in the A- chain and B-chain of nPS, respectively. The v1torsion angle forAsp35 changes from ) 75.20° to )171.65° and )89.25° in the A- chain and B-chain of nPS, and in the case of His37, ... Protein–ligand and water-mediated protein–ligand hydrogen bond interactions (broken lines) that stablize the pantoate molecules in site I and site II of nPS. Oxygen atoms of pantoate and water are...

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