... catecho-lamine vasoconstrictors and that the effect of Ala-Gln is asso-ciated with its capacity to induce HSP70 expression and attenuate release of pro-inflammatory cytokines and oxidizingspecies ... pathophysiological state, and despite considerable therapeutic advances, it remains a majortherapeutic challenge with a high incidence of mortality [1].Vascular hyporeactivity to catecholamine ... soft-ware (GraphPad Software, Inc., San Diego, CA, USA). Thevalues of PE Emax and median effective dose (EC50) weredetermined for each treatment group. Data are presented asmean ± standard...