Báo cáo y học: "Novel mutation in YMDD motif and direct neighbourhood in a child with chronic HBV-infection and clinical lamivudine and adefovir resistance - a scholarly case" docx
Báo cáo y học: "Novel mutation in YMDD motif and direct neighbourhood in a child with chronic HBV-infection and clinical lamivudine and adefovir resistance - a scholarly case" docx
... neighbourhood in a child with chronic HBV-infection and clinical lamivudine and adefovir resistance - a scholarly caseVerena Schildgen1,4, Susanne Ziegler2,3, Ramona L Tillmann4 and Oliver Schildgen*2,3AbstractContext: ... 125:29 2-7 .doi: 10.1186/174 3-4 22X- 7-1 67Cite this article as: Schildgen et al., Novel mutation in YMDD motif and direct neighbourhood in a child with chronic HBV-infection and clinical lami-vudine ... mutation was previously not reported and might also be associated with lamivudine resistance. Induction of isoleucine or valine in the YMDD motif results in a sterical hindrance, preventing lamivudine from...
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Báo cáo y học: "Left ventricular diastolic dysfunction of the cardiac surgery patient; a point of view for the cardiac surgeon and cardio-anesthesiologist" pptx
... persist, at least for the first threepostoperative hours after coronary artery bypass grafting[48,49]. In a similar way, Yamamoto et al by using classi-cal ECHO after coronary artery bypass grafting, ... surgeryFollowing coronary artery bypass grafting, DD is tempo-rarily deteriorated (expressed as a decrease in E-max and an increase in A- max of transmitral flow) [47]. This dete-rioration ... MR-myocar-dial tagging, radionuclide ventriculography) and invasivetechniques (micromanometry, angiography, conductancemethod). Typical findings of primary DD in chest radio-graph include absence...
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Báo cáo y học: "The Nordic Maintenance Care Program - Time intervals between treatments of patients with low back pain: how close and who decides" pps
... both in a survey of maintenance and non-maintenance carepatients treated by Danish and Norwegian chiropractorsDENMARKInitiativetaken byMaintenance carepatient (n = 103)Non-maintenance carepatients ... wo. In order to study the appointment pattern,patients’ past appointment was cross-tabulat ed againstthe next appointment, separately for MC patients and non-MC patients. To illustrate a possible ... Denmark and 20 in Norway.Number of maintenance care patientsThe range of MC patients per chiropractor in Denmarkwas 0 %-5 0% and the mean and median values were 22%.The range was 0% - 100% among...
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Báo cáo Y học: Novel protein phosphatases in yeast docx
... rcelona, Spain.E-mail: Joaquin.Arino@uab.esAbbreviations: MAP kinase, mitogen activated protein kinase; TOR,target of rapamycin; PP1, type 1 protein phosphatase; PP 2A, type 2A protein phosphatase; ... aggravated by deletion of PPZ2 [10]. Ppz1functionally interacts with the protein kinase C-activatedmitogen activated protein (MAP) kinase pathway, involved in maintenance of cellular integrity, that ... by PPT1 contains two distinctdomains: an N-terminal extension of almost 200 residues,characterized by four tetratricopeptides repeats (TPR), and a C-terminal domain that displays the typical...
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Báo cáo y học: "P5L mutation in Ank results in an increase in extracellular inorganic pyrophosphate during proliferation and nonmineralizing hypertrophy in stably transduced ATDC5 cells" pdf
... total Ank proteinby a quantitative ELISA assay using a peptide-directed poly-clonal antibody that was capable of reacting to exposed (thatFigure 1Transfection of ATDC5 cells with wild type and ... I: Up-regulated expression of carti-lage intermediate-layer protein and ANK in articular hyalinecartilage from patients with calcium pyrophosphate dihydratecrystal deposition disease. Arthritis ... col1 0a1 , sense primer 5' -taccacgtgcatgtgaaagg-3' and antisense primer 5' -ggagccactaggaatcctga-3' (productsize = 236 bp); and sox9, sense primer 5' -agt tga tct gaa gcgaga...
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Báo cáo y học: " Novel genetic analysis in Behçet’s disease" ppsx
... having identifiedpotential SNPs, validating the findings in each sampleEditorialNovel genetic analysis in Behçet’s diseaseGraham WallaceAcademic Unit of Ophthalmology, School of Immunity ... diseasecan take many forms in BD, and more detailed analysis will berequired when greater numbers are tested for these SNPs.There are certain caveats to the findings. Genome-wideanalysis (GWAS) ... maintenance of MHC class Imolecules on the cell surface and be linked to the patho-genesis of the disease. In subset analysis the UBASH3B SNP was more common in patients with ocular and vascular...
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Báo cáo y học: "Genome-wide analysis of the diatom cell cycle unveils a novel type of cyclins involved in environmental signaling" pptx
... CDKA and is active dur-ing both G1-to-S and G2-to-M transitions [19]. The plant-specific B-type CDKs contain a P [P/S]T [A/ T]LRE motif and are active during the G2 and M phases [19]. In animals,three ... Cip/Kip family in animals [51], or Kip-related proteins and SIAMESE pro-teins in plants [52,53]. CKIs are mainly low-molecular-weight proteins that inhibit CDK activity by tight associa-tion in ... (17337)Arath;CYCC1;2Arath;CYCC1;1Arath;CYCT1;4Arath;CYCT1;2Homsa;CYCD2Homsa;CYCD1Thaps (21159)Homsa;CYCG1Homsa;CYCG2Arath;CYCD4;1Arath;CYCD2;1Homsa;CYCJHomsa;CYCE2Arath;CYCB1;1Arath;CYCB3;1Thaps (36441)Phatr;CYCP6Phatr;CYCP4Phatr;CYCP1Phatr;CYCP5Phatr;CYCP3Phatr;CYCP2Phatr;CYCH1Phatr;CYCL1Phatr;CYCD1Phatr;CYCA/B;1Arath;SDSPhatr;CYC-likeThap...
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Báo cáo y học: " Novel venom gene discover Novel venom gene discovery in the platypusy in the platypus" pot
... these are expressed in venom gland alone and are classified as probable platy-pus venom tox ins. However, searches of alph a- latrotox-ins against the GenBank database do reveal ankyrinrepeat-containing ... WashingtonUniversity, overseen by RW and EM. SA and MM carried out mapping of the454 data to the genome and GO analysis of the 454 data and providedadvice on computational analysis. All authors read and approved ... McGrath, Amy Ly, Khaing Soe, RyanDemeter, Kevin Haub and Vincent Magrini, who provided invaluable training and advice on wet lab methodologies and data analysis. CW is supported by a Fulbright...
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Báo cáo y học: "Novel model for end-neuroma formation in the amputated rabbit forelimb" ppsx
... body temperature was maintained using a circulat-ing-water heating pad.An elliptical skin incision was made around the leftforelimb girdle, encompassing the axillary fold medially in anticipation ... Pharmaceuticals Inc., Richmond, VA) and then sedated with ketamine 4 0-4 5 mg/kg intramuscu-larly (IM) (Ketaset®, Fort Dodge Animal Health, Over-land Park, KS) and xylazine 5-7 mg/kg IM (X-ject ... analysis. Using a semi-automated t echnique, characterized by dynamic thresh-olding and manual fiber elimination, [10,11] each nervewas analyzed to determine the nerve cross-sectionalarea,...
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Báo cáo y học: "Novel anti-inflammatory role of SLPI in adipose tissue and its regulation by high fat diet" pptx
... -AT GGGTCAGAAGGACTCCTACG-3’ and anti-sense, 5’-AGTGGTACGA CCAGAGGCATAC-3’;TNFa,5’ -AG CCCCCAGTCTGTATCCTT-3’ and 5’ -CTCCCTT TGCAGAACTCAGG-3’. Quantification of tran-scripts was done with the ... 5’-GAGCATTGGAAATTGGGGTA-3’ for the sense and antisense primers, respectively (14); SLPI, sense,5’ -TGCTTAACCCTCCCAATGTC-3’ and antisense,5’ -AA TGCTGAGCCAAAAGGAGA-3’ ; b-actin sense,5’ -AT ... plasminogen activator inhibitor (PAI) 1[6].Inflammatory cytokines produced in adipose tissue actlocally and systemically to amplify the inflammatory cas-cade and oppose insulin signaling in...
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