báo cáo khoa học: " Over-expression of miR172 causes loss of spikelet determinacy and floral organ abnormalities in rice (Oryza sativa)" pps

... article Over-expression of miR172 causes loss of spikelet determinacy and floral organ abnormalities in rice (Oryza sativa)Qian-Hao Zhu, Narayana M Upadhyaya, Frank Gubler and Chris A Helliwell*Address: ... timing and/ or positioning of the floral organ meristems are interrupted by over-expression of miR172b, indicating that a proper expression of miR172 target genes is important in specification of ... of 13(page number not for citation purposes)Changes in the number of floral organs and floral identity in plants over-expressing miR172bFigure 6Changes in the number of floral organs and floral...

Báo cáo khoa học: Frataxin deﬁciency causes upregulation of mitochondrial Lon and ClpP proteases and severe loss of mitochondrial Fe–S proteins pot

... weeks of age were analyzedby immunoblotting with antibodies against Lon and ClpP. Immunolabeled protein bands of interest were then quantified using a ChemiDocimaging system and QUANTITY ONE software ... vitro, Lon binds to specific regions of the light-strand and heavy-strand promoters of mitochondrialDNA [36,37], and this was recently confirmed in livingcells, pointing to another function of this ... deficiencies in the activ-ity of specific proteases, which have important roles in protein turnover and in the removal of damaged or unneeded protein. In this study, usingthe muscle creatine kinase...

Báo cáo khoa học: DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine pptx

... biologicalactivity of harmine in vivo. Interestingly, our resultsshow that harmine not only inhibits the protein–ser-ine ⁄ threonine kinase activity of the mature enzyme,but also the tyrosine autophosphorylation ... phosphorylation of Thr125 is also blocked by harmine, conﬁrm-ing the use of this b-carboline alkaloid as a potent inhibitor of DYRK1A in cells. We show that harmine not only inhibits the protein–serine ... number of neurons during post-embryonic neurogenesis: muta-tion of minibrain causes reduction of the size of theoptic lobes and central brain hemispheres [4], whereasmice lacking one copy of the...

Báo cáo khoa học nông nghiệp: Phân tích QTL tính trạng chống chịu khô hạn trên cây lúa Oryza sativa L.

... assited selection to introgress rice QTLs controlling root traits into an indian upland rice varieties. Thomashow MF. 1998. Role of cold-responsive genes in plant freezing tolerance. Plant ... 110:249-257 Xu JL, HR Lafitte, YM Gao, BY Fu, R Torres, and Z Kang. 2005 QTLsfordroughtescapeand toleranceidenti?edinasetofrandom.Introgressionlinesofrice.TheorApplGenet(2005)111:16421650 Zhang J, ... Sticklen. 2002. Competence of oat (Avena sativa L.) shoot apical meristems for integrative transformation, inherited expression, and osmotic tolerance of transgenic lines containing hva1. Theor Appl...

báo cáo khoa học: "Pulmonary histoplasmosis presenting as chronic productive cough, fever, and massive unilateral consolidation in a 15-year-old immunecompetent boy: a case report" potx

... other fluids in thediagnosis of disseminated histoplasmosis; however, opti-mal diagnostic yield is the result of testing both urine and serum [15]. Histopathological examination, as in our case, ... details1Department of Medicine, Weill Bugando University College of HealthSciences, Mwanza, Tanzania.2Department of Medicine, Bugando MedicalCentre, Mwanza, Tanzania.3Department of Pathology, Weill BugandoUniversity ... review and casehistories of Histoplasma capsulatum var. duboisii infections in HIV-infected patients. Emerg Infect Dis 2007, 13:1647-1652.9. Goodwin RA Jr, Des Prez RM: Pathogenesis and clinical...

Báo cáo khoa hoc:" Human pluripotent embryonal carcinoma NTERA2 cl.D1 cells maintain their typical morphology in an angiomyogenic medium" pps

... restrictedto developing myocardium. Cripto knockout is lethal in mouse and its inactivation in vivo results in the loss of detection of some cardiac transcripts, such as, alpha myosinheavy chain (α-MyHC), ... characteristics, as theincrease in nuclear/cytoplasm volume ratio, the flattening of the cells, the prominent nucleoli (Figure 1), the polym-erized actin organization (phalloidin staining) and ultrastructural ... source of blast-ocele-like fluid. Differentiation 1990, 43(1):51-58.8. Soprano DR, Soprano KJ, Wyatt ML, Goodman DS: Induction of the expression of retinol-binding protein and transthyretinin...

Báo cáo khoa học: "Recently published papers: An ancient debate, novel monitors and post ICU outcome in the elderly" potx

... P-C:Timing of tracheostomy as a determinant of weaning success in critically ill patients: a retrospective study. Crit Care 2005, 9:R46-R52.4. Blot F, Melot C: Indications, timing, and tecniques of ... Hospital. A total of 163 patients were included and divided into two groups:successful weaning and failure to wean. Interestingly, thestudy discusses rates of associated complications of bothpercutaneous ... several interesting points. First, theirdefinition of early tracheostomy was any time during the first3 weeks after intubation. Second, early tracheostomy wasconsidered more often in nonteaching...

Báo cáo khoa học: "limits for blood delivery via femoral vein access and a potential alternative in an experimental setting in anesthetized pigs" pps

... to2 liters/minute and were independent of the subgroup or theindividual BW. Thus, using a range of BW of 35 to 50 kg in immature domestic pigs and a bolus volume load at the begin-ning was apt ... patientslacking right jugular vein access with tip positioning of large-French dual-lumen catheters in the right atrium, it would be of interest to obtain clinical data re-evaluating the 'dual-veinapproach' ... infections. Placed in a central vein position, side holesmay lead to intima attachment, reducing Qa and increasing therisk of thrombus formation. Thus, by the introduction of a mod-ified Seldinger's...

Báo cáo y học: "Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences" ppsx

... different versions of an underlying program or library. To ease the burden of installing and administering tool dependencies, w eare pursuing the approach of building virtual machineimages that ... 13number of high-profile Galaxy servers in use, inclu dingservers at the Cold Spring Harbor Laboratory and theUnited States Department of Energy Joint GenomeInstitute.Individuals and groups ... ensuring thatanalysis is documented in a form another scientist canreproduce requires learningandpracticingsoftwareengineering skills (Note that neither programming norsoftware engineering...

Báo cáo khoa học: Overexpression of human histone methylase MLL1 upon exposure to a food contaminant mycotoxin, deoxynivalenol docx

... McCulloch CA(2002) Interaction of p38 and Sp1 in a mechanicalforce-induced, beta 1 integrin-mediated transcriptionalcircuit that regulates the actin-binding protein ﬁlamin-A. J Biol Chem 277, ... Src kinases and induces in am-mation and oxidative stress-responsive genes such asinterleukins and cyclooxygenase [32,36,40–42]. UsingRT-PCR analysis, we also observed that interleukin-8 and ... humancells.Src kinase inhibitor suppressed the DON-inducedupregulation of MLL1To understand potential mechanism of DON-mediatedupregulation of MLL1 and Hox genes, we examinedthe involvement of different...

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