... TOP-containingmRNAs encoding polypeptides involved in mRNAtranslation, including elongation factors 1 and 2 and ribosomal protein S6 kinases [15].The PABP1 gene behaves like an early response gene, ... step in protein syn-thesis, and is usually regulated by several importantinitiation factors, including poly(A)-binding protein(PABP) 1 and eukaryotic initiation factors (eIFs) 4E,4G, 2a, and ... of both PABP1 and eIF4Goccur following heat shock, and suggest that seques-tration of both PABP1 and eIF4G within the cellnucleus may be an important contributing factor in suppressing translation...