... therapy, in mothers withthyroidectomy during pregnancy, in mothers with aprevious history of ablation therapy for Graves’ hyperthyr-oidism, and in the presence of fetal tachycardia and incidental ... with the signs and symptoms ofthyroid disease. Most clinicians are aware of other signs and symptoms of hyperthyroidism that indicate thyroiddisease and are not common in pregnancy, such asweight ... long-standing hyperthyroidism, large goiters, orsignificant exophthalmos and, if they remain untreated,they may worsen in the last trimester and toxemia, cardiacfailure, and even ‘thyroid storm’...