Báo cáo y học: " Retrospective seroepidemiology indicated that human enterovirus 71 and coxsackievirus A16 circulated wildly in central and southern China before large-scale outbreaks from 2008" docx
Báo cáo y học: " Retrospective seroepidemiology indicated that human enterovirus 71 and coxsackievirus A16 circulated wildly in central and southern China before large-scale outbreaks from 2008" docx
... al.: Retrospective seroepidemiology indicated that human enterovirus 71 and coxsackievirus A16 circulated wildly in central and southern China before large-scale outbreaks from 2008.Virology Journal ... 7:300http://www.virologyj.com/content/7/1/300Page 2 of 6RESEARC H Open Access Retrospective seroepidemiology indicated that human enterovirus 71 and coxsackievirus A16 circulated wildly in central and southern China before ... provinces.Conclusions: This report confirmed that HEV71 and CVA16 had wildly circulated in a couple provinces in China before the large-scale outbreaks from 2008. This finding also suggests that...
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Báo cáo y học: "SOX9 transduction of a human chondrocytic cell line identifies novel genes regulated in primary human chondrocytes and in osteoarthritis" docx
... cells, in primary chondrocytes, and also in OA cartilage. SRPX generally correlated withSOX9, except during chondrocyte dedifferentiation, whichmay indicate that other factors predominantly influence ... immunoblotting using an anti-SOX9 goat polyclo-nal antibody (H-90, Santa Cruz Biotechnology, Calne UK). Human articular chondrocytes were isolated from cartilage onOA knee joints and maintained in ... being unable to confirm any regulation by SOX9 in SW1353 by real time PCR, and with its expression unaffected in primary chondrocytes by the transition to monolayer culture,it was interesting...
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Báo cáo y học: "NSP2 gene variation of the North American genotype of the Thai PRRSV in central Thailand" ppt
... Zhang X, Yoo D, Wang J:Genetic variation and pathogenicity of highly virulent porcinereproductive and respiratory syndrome virus emerging in China. ArchVirol 2009, 154:1589-1597.23. Amonsin A, ... Accordingto the farm history, Type 2 PRRSV infection was ende-mic and clinically stable in those selected farms. Sam-ples were collected when the appearance of respiratorysymptoms in suckling and/ or ... respiratory syndrome virus (PRRSV) is a major swine pathogen causing economic losses in the swine industry almost worldwide. PRRSV has been divided into 2 genotypes, the European (Type 1) and North...
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Báo cáo y học: "Accelerated hand bone mineral density loss is associated with progressive joint damage in hands and feet in recent-onset rheumatoid arthritis" ppt
... positive in 62% of the patients and 70% had at least one erosion in hands and feet.Changes in hand BMD and joint damage in hands and feet in the first yearThe median (interquartile range (IQR)) hand ... the sys-temic, the local effect of high pro-inflammatory cytokinelevels originating in adjacent active arthritis of the handjoints. On the other hand, it may also be partiallyexplained by methodological ... RA patients, baseline and 1-year hand BMD was measured in metacarpals 2-4 by digital X-ray radiogrammetry. Joint damage in hands and feet were scored in random order according to the Sharp-van...
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Báo cáo y học: "An updated study-level meta-analysis of randomised controlled trials on proning in ARDS and acute lung injury" pps
... an increase in major airway complications. The current study-levelmeta-analysis confirms and reinforces recent findings ofindividual patient data meta-analyses made by Sud and colleagues and ... for the most severe hypoxemic patients wererecently confirmed by the meta-analyses from Sud and colleagues and from Gattinoni and colleagues showingreduced mortality rate in patients with PaO2/FiO2ratio<100 ... (Prone-Supine Study), Gattinoni and colleagues highlighted in a post-hoc analysis that pronepositioning reduced the 10-day mortality of patientswith the highest disease severity (Simplified Acute Phy-siology...
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Báo cáo y học: " Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions" pps
... genes by flow cytometry and immunocytochemistryFigure 4Validation of selected genes by flow cytometry and immunocytochemistry. (a) Flow cytometry analysis of prostate cancer cells co-stained with ... University of York, Heslington, York YO10 5DD, UK. §York Centre for Complex Systems Analysis, Department of Biology, University of York, York YO10 5YW, UK. ¶Department of Urology, York Hospital, ... The Biocentre, Innovation Way, York Science Park, Heslington, York YO10 5NY, UK. †YCR Cancer Research Unit, Department of Biology, University of York, York YO10 5YW, UK. ‡Hull York Medical...
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Báo cáo y học: "Genetic analysis of the human infective trypanosome Trypanosoma brucei gambiense: chromosomal segregation, crossing over, and the construction of a genetic map" doc
... phenotypic characteristics, most notably in their ability to infect humans. Indeed, the T. b. gambiense and T. b. brucei strains examined here not only differ in termsof human infectivity and ... lines were establishedeither by directly cloning metacyclic stage trypanosomes in individual immuno-suppressed mice or by cloning from bloodstream stage infections derived directly from feedinginfected ... identifying genes that determine these traits. The value of a genetic map foridentifying loci that effectuate particular phenotypes is pri-marily determined by the recombination frequency of...
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Báo cáo y học: " Citrullinated proteins: sparks that may ignite the fire in rheumatoid arthritis" ppt
... were initially investigated, a recent follow up of that study [28] showed that citrullinated fibrin may also bepresent in synovial tissue of patients with other forms ofjoint inflammation. By ... citrullination. In summary, although many different citrullinated proteinsmay be present in the RA synovium, thus far three proteinscan be considered as candidate autoantigens in RA:citrullinated ... in the inflamed synovium,especially in the synovial fluid. Because granulocytes havea lifespan of only about 3 days, they will die in largenumbers at the site of inflammation, which may triggerhistone...
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Báo cáo y học: "Expert agreement confirms that negative changes in hand and foot radiographs are a surrogate for repair in patients with rheumatoid arthritis" pot
... repair by theexperts viewing only the joint-of-interest in Exercise I; in theremaining six cases, the two independent readers did notscore repair in the joint-of-interest, which was in agreementwith ... analysis that included all the cases more closelyreflects reality in clinical studies since there will always becases that are equivocal. The analysis that excluded thesecases indicates that where ... constrained by thenumber of joints with damage, and probably also by the levelof damage in those joints. In fact, data from animal studiesclearly indicate that once the matrix is resorbed the rate and extent...
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Báo cáo y học: "New data favouring that neurotrophins are of importance in arthritis" pot
... in fibroblast-like synoviocytes, as seen by ELISAanalysis on culture supernatant. The authors concluded that infiltrating T lymphocytes and myeloid cells are the mainsources of NGF in the inflamed ... present in the synovial tissue and on chondrocytes. Theimportance of neurotrophins in joints should be further studied,including examinations on the efficacy of interfering with theireffects in ... Neurotrophins are also of importance as factors that promote growth and survival of neurons, and they may beinvolved in the pathogenesis of pain. In accordance with the findings of Barthel and collaborators[1],...
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