... [6,7],FERM and PDZ-domain-containing 2 (FRMPD2) [8] and Ras guanine exchange factor (RasGEF) very-KIND (v-KIND, or kinase noncatalytic C-lobedomain containing 1) [9]. The KIND domain in theseproteins ... protein kinase regulatory subunitRII binding domain, the central domain (CD) and the microtubule-binding domain (Fig. 3A) . To deter-mine the v-KIND-binding region in MAP2, we firstdivided MAP2 into ... and regulatorysubunits, implying that the KIND domain, an atypicalnoncatalytic C-lobe, is involved in the interaction with signaling proteins [3,5,10]. However, the structural and functional...