báo cáo khoa học: " High risk behaviors of injection drug users registered with harm reduction programme in Karachi, Pakistan" docx

... CentralPage 1 of 6(page number not for citation purposes) Harm Reduction JournalOpen AccessResearch High risk behaviors of injection drug users registered with harm reduction programme in Karachi, ... (parents, siblings)Yes 30 (18.6)No 131 (81.3)Average age of initiation of drugsAge of initiation of drugs 15.9 yearsAverage time initiation of injection 4.4 years Injection drug use (last ... month)Average number of drug injections per day 2.3 {range 1–9 injections)Previous day's injection with a new syringe 153 (95)Shooting drugs in group sharing syringes 128 (79.5)Using anyone else's...

báo cáo khoa học: " Acquired A amyloidosis from injection drug use presenting with atraumatic splenic rupture in a hospitalized patient: a case report" potx

... linear vegetation onthe prosthetic aortic valve and a possible ring abscesswithout evidence of aortic insufficiency. Therapy with intravenous ciprofloxacin, gentamicin and levofloxacinwas initiated.On ... likely resulting from chronic injection drug use.Case presentationA 58-year-old Caucasian man with an extensive history of injection drug use was hospitalized with a diagnosis of infective endocarditis ... spleen.Conclusion: In patients with chronic inflammatory conditions, including the use of injection drugs, whoexperience acute onset of left upper quadrant pain, the diagnosis of atraumatic splenic...

Báo cáo khoa học: A truncated form of DNA topoisomerase IIb associates with the mtDNA genome in mammalian mitochondria doc

... replication of theleading strand was thought to begin ﬁrst, producing anexpanding displacement (D)-loop prior to the initiation of lagging strand synthesis. Instead, synthesis of leading andlagging ... 60 min in a Ti50.2 rotor. For experimentsrequiring intact mtDNA–protein complexes, the dark brownpellet (containing complexes of mtDNA and protein) wasre-suspended in 10 mL of Buffer A using ... are inhibited by novobiocin, and by a variety of useful anticancer drugs including adriamycin, 4¢-(9-acrid-inylamine)methanesulfon-m-anisidide (m-AMSA), etopo-side (VP-16), and ellipticine...

Báo cáo khoa học: "pH-dependent modulation of intracellular free magnesium ions with ion- selective electrodes in papillary muscle of guinea pig" ppt

... ...

Báo cáo khoa học: " High-risk surgical stage 1 endometrial cancer: analysis of treatment outcome" pdf

... recurrence. In theGOG study [11], a " ;high intermediate" group was definedby a combination of risk factors that included advancedage, lymphovascular invasion, outer-third invasion, ... the higher risk grouphad a 13% risk for local-regional failure. The high inter-mediate risk patients were also at risk for failing distantly, with a 48-month observed distant failure rate of ... applications with a mediandose of 24 Gy (range 20–30 Gy). The point of prescriptiondose used in the vaginal brachytherapy was the vaginalsurface or to 5 mm of the surface of applicator when vag-inal...

báo cáo khoa học: " High HCV seroprevalence and HIV drug use risk behaviors among injection drug users in Pakistan" doc

... region bordering Afghanistan.However, in 2003, HIV/AIDS officials in Sindh reportedan outbreak of HIV infection among injection drug users (IDUs) in a prison located outside of Karachi, in whichamong ... 0.3 (0.1–1.0)* Jerking refers to the practice of drawing blood into the syringe while injecting drugs.** Includes professional and non-professional medical injections† Includes only those ... believed to prevent symptoms of heroin withdrawal[28].Although the practice of jerking alone would not appearto confer an elevated risk of infection in the absence of sharing injection equipment,...

Báo cáo khoa học: "High throughput evaluation of gamma-H2AX Dane Avondoglio1, Tamalee Scott1, Whoon Jong Kil, Mary " ppsx

... andreplaced with drug- free media. Ten to fourteen days afterseeding, colonies were stained with crystal violet, thenumber of colonies containing at least 50 cells was deter-mined, and surviving fractions ... evaluated three times in 30 nuclei per treatment per experiment. (B) Plot of the linear dynamic range of the immunofluorescent staining assay. (C) Plot of the linear dynamic range of the MSD Assay.BioMed ... important information, there isstill a need for an analytical high throughput assay that iscapable of screening radiomodifying drugs across diversecell lines and in vivo tissue. We show that using...

báo cáo khoa học: " High-throughput analysis of chromosome translocations and other genome rearrangements in epithelial cancers" pdf

... mutations, not only increasing expression of a protein but also changing its activity, subcellular localiza-tion or binding speciﬁcity [1,2]. Such fusion genes are also clinically important, ... SL, Raby S, Ichimura K, Collins VP, Carter NP, Edwards PA: Array painting reveals a high frequency of balanced translocations in breast cancer cell lines that break in cancer-relevant genes. ... large-scale survey of somatically acquired structural variation in the genomes of cancers, with the explicit goal of discovering genes disrupted and fused at chromosome breakpoints. e authors...

Tài liệu Báo cáo khoa học: Isolation and characterization of four type 2 ribosome inactivating pulchellin isoforms from Abrus pulchellus seeds docx

... shown capable of inhibiting 90% proteinsynthesis within 4 h, was used in all preincubations. Eachtoxin was mixed with increasing concentrations of GalNAc in DMEM ⁄ FCS for 30 min. at 37 °C. ... mayreﬂect suboptimal binding of GalNAc in one or bothbinding pockets of P I. However, in striking contrast with the rescue of protein synthesis observed for P Iand P II, protection against P III and ... chains of ricin, a toxicprotein inhibiting protein synthesis. Biochemistry 12,3121–3126.21 Olsnes S & Pihl A (1973) Isolation and properties of abrin: a toxic protein inhibiting protein...

Tài liệu Báo cáo khoa học: Glucuronate, the precursor of vitamin C, is directly formed from UDP-glucuronate in liver pptx

... also be involved in theformation of glucuronate. Interestingly, vitamin C for-mation is induced in Gunn rats by phenobarbital [8],an inducer of UGT2s, which is indirect evidence forthe involvement ... effect in fact) of about the same order of magnitude as in intact hepatocytes. This inhibitory effect of ATP-Mgwas no longer present in washed liver microsomes,but could be restored in this ... decrease in the inhibition was observed with time in the case of valproate, which was more slowly metabolized. Inhibi-tion of glucuronate formation was also observed with other substrates of glucuronidation...

Xem thêm