... with HIV-1 To assess whether the expression of HIV-1 receptor com-plex on cotton rat cells render them permissive for viralinfection, the different receptor expressing clones and the parental ... otherrodents have and that virus entry is the major hurdle for HIV-1 to replicate in this species, clones of the cotton ratcell lines VCRT (C17) and CCRT (C4, C5, and C6)expressing hCD4 and ... of the genome[22,23]. Although these are not the most favorable sites for integration[24], the inser-tion in their vicinity occurs most likely due to the abun-dance of these sequences in the...