... Arinobu Y, Akaiwa M, Enomoto T,Dake Y, Kawai M, Sasaki S, Hamasaki N, Izubara K, Shirakawa T,Hopkin JM: Variants of STAT-6 (signal transducer and activator of transcription 6) in atopic asthma. ... Mitsuyasu H, Izuhara K, Mao XQ, Gao PS, Arinobu Y, Enomoto T,Kawai M, Sasaki S, Dake Y, Hamasaki N, Shirakawa T, Hopkin JM:Ile50Val variant of IL4Rααupregulates IgE synthesis and asso-ciates ... significant increase in airway hyper-responsiveness that was associated with the elevation of sputum eosinophil numbers [17]. A variety of findingssuggest that atopic individuals have altered...