... frequency of Tax express-ing cells (Tax+CD4+/CD4+) in the HAM/TSP patients and in the ACs in each of the 6 bins was calculated. The teststatistic, "number of bins in which the proportion of CD4+ ... 2Department of Zoology, University of Oxford, Oxford OX1 3PS, UK, 3Department of Immunology, Graduate School and Faculty of Medicine, University of the Ryukyus, Okinawa 903-0215, Japan and 4Department ... stable. Using the result-ing distribution, the probability of observing the test sta-tistic under the null hypothesis was estimated and doubled to obtain a two-tailed P value. The grouping of subjects...