Báo cáo y học: " Cocaine Addiction Treatments to improve Control and reduce Harm (CATCH): New Pharmacological Treatment Options for Crack-Cocaine Dependence in the Netherlands" doc
Báo cáo y học: " Cocaine Addiction Treatments to improve Control and reduce Harm (CATCH): New Pharmacological Treatment Options for Crack-Cocaine Dependence in the Netherlands" doc
... et al.: Cocaine Addiction Treatments to improve Control and reduce Harm (CATCH): New Pharmacological Treatment Options for Crack -Cocaine Dependence in the Netherlands.BMC Psychiatry 2011 11:135.Submit ... in terms ofreduced cocaine use, craving, severity of dependence and delinquent behaviour, and dexamphetamine SR wa sfoundtoattenuatecocaineuseandimprovetreatmentretention in combined cocaine ... rationale for sub-stitution treatment for cocaine dependence is similar to that for other addictions (nicotine replacement therapy in nicotine dependence, methadone and buprenorphine in opioid dependence) :...
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Báo cáo Y học: Complexation of ytterbium to human transferrin and its uptake by K562 cells pot
... apo-Tf in the specific iron binding site and twotyrosines are involved in binding of Yb3+ in both the N- and C-lobe as the case for Fe3+. The X-ray crystal structure ofSm2-lactoferrin revealed ... by Fe3+.Interestingly, the binding to the N-lobe is kineticallyfavored. The binding of Yb2-Tf to K562 cell membranes(TfR) was demonstrated and was weaker than that of Fe2-Tf and only ... De242increaseslinearly with the increase of Yb/apoTf ratio (r)uptoavalue of r ¼ 1. The results indicated that Yb3+bound to tyrosine residues of the Fe3+-binding sites and induceddeprotonation....
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Báo cáo y học: "Innovative combination strategy to enhance effect and diminish adverse effects of glucocorticoids: another promise" pot
... targeting of gluco-corticoids to inflammatory sites using polyethylene glycolliposomes as a vector, increasing local levels and reducingsystemic concentrations of glucocorticoids and thus limiting the ... laboratory models, rats, and mice are not patients and the glucocorticoid mechanismsleading to effects and adverse effects are manifold.Ultimately, the proof of the pudding is in the eating. ... actions(especially at higher doses) and the genomic actionstransrepression and transactivation are not fully synonymouswith inflammatory and immunosuppressive activity and withadverse effects, respectively....
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Báo cáo y học: "Assisted assembly: how to improve a de novo genome assembly by using related species" pptx
... from arandom ligation in the library construction process - joining the contigs would carry a roughly 1% risk of introducing afalse join into the assembly. Now suppose both reads of the pair ... at the scaffolding level.We then devised the following statistical validation test to determine the quality of any given assembly against a finishedor high quality draft assembly. We randomly ... Supposing that the group is assigned to a contig, we then take all the readsfrom the group that are not already in the contig, and align the reads one by one to the contig. If there is an end -to- end...
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Báo cáo y học: " COPD diagnosis related to different guidelines and spirometry techniques" ppsx
... ofearly detection and active smoking intervention is empha-sized and it therefore seems prudent to also include milddisease (as in ERS and GOLD) in the definition of COPD in order to intensify the ... Walsh-Ingelström, Lund, for their work in examining the study subjects. Financial funding for this study was received from the research department of AFA (former AMF) insur-ance company, Stockholm, ... for citation purposes)aim of the study was to determine the prevalence ofCOPD using the definitions and recommendations from the European Respiratory Society (ERS) from 1995, the National Institute...
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Báo cáo y học: " Early management after self-poisoning with an organophosphorus or carbamate pesticide – a treatment protocol for junior doctors" potx
... thank the doctors of the Ox-Col Poisoning Study Team for their excellent work, patient care, and feedback about the protocol; the Direc-tors, and medical and nursing staff of the study hospitals ... confusion and pyrexia. However, confusion and/ or pyrexia in the absence of bowel sounds suggests that they are due to atropine toxicity and will respond to a reduction in the rate of atropine administration.Alcohol ... atropine therapy is to clear the chest and reach the end-points for all five parameters.2. There is no need to aim for a heart rate of 120–140 beats/min. This suggests atropine toxicity rather...
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Báo cáo y học: "Maternal Outcomes According to Placental Position in Placental Previa"
... ultrasonography and the findings of surgery were reviewed in all patients. To compare maternal outcomes, the hemoglobin level of prior to surgery, 1 day after surgery, and 3 days after surgery, the ... retro-spectively, and the previa cases with the placental main body located in the anterior uterine body were assigned as the anterior group, and those with the placenta located in the posterior ... posterior portion of the uterus (posterior group). And then they are com-pared to each other. Logistic regression was used to control for confounding factors. Results: In the anterior group,...
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Báo cáo y học: " Carotid Intima-media thickness in childhood and adolescent obesity relations to abdominal obesity, high triglyceride level and insulin resistance"
... adiposity-associated inflammatory factors such as C-reactive protein (CRP), interleukin (IL)-6 and tumor necrosis factor (TNF)-α may play a role in promoting adverse vascular outcomes. The intima ... Second, we used the standard of WC in Beijing rather than Zhe Jiang province, which might influence samples selection. Finally, the IMT may also probably be influenced by other risk factors which ... tested in our study. In conclusion, atherosclerosis begins in obese children and adolescents, and this tendency is inten-sified in the presence of MetS. Obesity especially ab-dominal obesity,...
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Báo cáo y học: " A Practical Approach to Managing Patients with HCV Infection"
... HCV Infection 1) History Obtaining a thorough clinical history is important as the initial step in consideration for treatment. The history can provide clues regarding the timing of HCV infection ... accuracy. Current standard therapy includes a combination of pegylated interferon and ribavirin. Response rate is approximately 40% for genotype 1 and 80% for genotypes 2 and 3, respectively. Successful ... potential treatment candidacy is an important initial step in the management of chronic HCV infection as not all individuals may need or qualify for the treatment. Understanding the natural history,...
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Báo cáo y học: "A Practical Approach to Management of Chronic Hepatitis B"
... made in managing HBV infection, challenge remains in optimizing HBV therapy. First, further understanding HBV dynamics and correlation of the level of HBV replication with liver injury will be invaluable ... prior to these treatments is associated with reduced frequency and severity of hepatitis B flare and improved survival in these patients [26, 29]. HBV Infection and Pregnancy Both LAM and ADV ... with improved histology. Therefore, a pre-HBV treatment liver biopsy is usually preferred by most hepatologists. However, for those with clear-cut indications for HBV treatment, a liver biopsy...
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