báo cáo khoa học: " ’It’s risky to walk in the city with syr

báo cáo khoa học: " ’It’s risky to walk in the city with syringes’: understanding access to HIV/AIDS services for injecting drug users in the former Soviet Union countries of Ukraine and Kyrgyzstan" ppt

... explanatory insights into the problems of accessing HIV/AIDS services. The aim was to develop a better understanding of the nat- ure and complexity of factors that obstruct access rather than to ... said they valued this ‘peer -to- peer’ princi- ple. For example, a former client and volunteer in Ukraine explained: ‘ as a former injecting drug user and...

Ngày tải lên : 11/08/2014, 14:21

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Tài liệu Báo cáo khoa học: AcmA of Lactococcus lactis is an N-acetylglucosaminidase with an optimal number of LysM domains for proper functioning ppt

... differences. In conclusion, the number of LysM domains present in the protein determines the binding efﬁciency of the protein, with optimal binding when three LysM domains are present. The results of the ... amidases, hydrolyzing the bond between the glycan chain and the peptide side chain, and peptidases of varying speci city. AcmA is the major autolysi...

Ngày tải lên : 19/02/2014, 18:20

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Báo cáo khoa học: Human mesotrypsin exhibits restricted S1¢ subsite speciﬁcity with a strong preference for small polar side chains docx

... responsible for the resistance of mesotrypsin against canonical trypsin inhibitors [3–5]. To determine the role of Arg198 in the resistance of mesotrypsin against a1AT, Arg198 was substituted with Gly, the ... obstruc- tion of the S1¢ site. The original objective of this study was to test whe- ther the serpin inhibitory mechanism can overcome the inhibitor...

Ngày tải lên : 30/03/2014, 10:20

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Báo cáo khoa học: It’s cheap to be colorful Anthozoans show a slow turnover of GFP-like proteins potx

... photo- conversion involves cleavage of the polypeptide chain into two fragments of  20 and  8 kDa [6,29,40,42]. Therefore, the amount of both fragments is indicative of the amount of the red form. ... radiation in vivo and in situ. In the absence of photoconverting light, we subsequently tracked degradation of the red-converted forms of the two protei...

Ngày tải lên : 30/03/2014, 09:20

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báo cáo khoa học: " It''''s time for Canadian community early warning systems for illicit drug overdoses" pdf

... characteristics of the substance and the potential risks, the better able they are to make informed choices about their drug use. Involving people with addic- tion in the reporting and disseminating of overdose ... source, and avoid mixing drugs with simi- lar effects. Evaluation of a cohort of injection drug users in Vancouver found the following facto...

Ngày tải lên : 11/08/2014, 18:20

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Tài liệu Báo cáo khoa học: Afﬁnity and kinetics of proprotein convertase subtilisin ⁄ kexin type 9 binding to low-density lipoprotein receptors on HepG2 cells docx

... reac- tion in which the ﬁrst binding step, representing binding to the EGF-A domain, is followed by binding of PCSK9 to a second site within the receptor. In this model, dimeric and monomeric receptor ... PCSK9 binding to HepG2 cells. First, the number of LDLRs on HepG2 cells increased following growth in the absence of lipo- proteins, and there was a corresp...

Ngày tải lên : 14/02/2014, 14:20

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Tài liệu Báo cáo khoa học: Structural and mechanistic aspects of ﬂavoproteins: photosynthetic electron transfer from photosystem I to NADP+ doc

... approach and colinear orientation of the N5 of the ﬂavin, the hydride to be transferred, and C4 of the nicotinamide. In FNR, displacement of the C-terminal Tyr appears to be required for the interaction ... protein– ﬂavin complexes and tailor the midpoint potentials in these proteins, as well as many details of the binding and electron transfer to...

Ngày tải lên : 18/02/2014, 11:20

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Tài liệu Báo cáo khoa học: It is all about resolution Meeting report based upon presentations at the 10th International Global BioMillennium 2006 symposium on molecular cell biology (Tbilisi, Georgia) docx

... developmental regulation of gene expression. Certain SR and hnRNP proteins shuttle continuously between the nucleus and the cytoplasm. Interestingly, hnRNP A1 binds to and is necessary for the processing of a cluster ... Ger- many). In the absence of interferon, STAT2 perma- nently and rapidly shuttles between the cytoplasm and the nucleus. A region in the...

Ngày tải lên : 19/02/2014, 02:20

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Tài liệu Báo cáo khoa học: Aldehydes release zinc from proteins. A pathway from oxidative stress⁄lipid peroxidation to cellular functions of zinc pptx

... signaling and gene expression. Results Aldehydes release zinc from zinc-binding proteins The effect of aldehydes on the zinc-binding capacity of zinc proteins was assayed by employing spectropho- tometry ... functions of zinc and MT against ethanol toxicity Both zinc and MT protect the liver and the heart against the toxic effects of ethanol [45–47]. The above resu...

Ngày tải lên : 19/02/2014, 06:20

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Tài liệu Báo cáo khoa học: Interactions between M proteins of Streptococcus pyogenes and glycosaminoglycans promote bacterial adhesion to host cells pdf

... mediate binding to proteins involved in host defence. Known relevant ligands for GAGs include growth factors, cytokines and other mediators of in ammation [3]. Hence, trapping of these mediators ... to the A–B3 region, IgGFc-binding to the S-domain, and albumin-binding to the C-repeats [31]. Recombinantly expressed fragments rA–S and rS–C3 are indicated. (D) The...

Ngày tải lên : 20/02/2014, 11:20

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