... World
Health Organisation following the landmark report of
the Commission on Health Research for Development
[16], has revised the term to research for health in an
attempt to emphasise public -health ... [EUR
22700].
doi:10.1186/1744-8603-7-5
Cite this article as: McCarthy: European health research and
globalisation: is the public-private balance right? Globali...
... with
the three other NIHR SDO Programme evaluation teams.
Discussion
The rationale underpinning the investment in the
CLAHRC initiative and the theory on which they have
been establ ished is that ... applicable health
research that is actually used in practice is theoretically and intuitively appealing; however the evidence for it is
limited. Our evaluation is de...
... ele-
ments of a historical perspective and the application of
agency theory.
Agency theory helped to understand the impact of
GHIs on the overall health aid scenario in Uganda,
rather than specific ... compatible with the alignment agenda
expressed by the Paris Declaration.
In themselves these insights fail to explain the conflict
among different aid mechanisms and with the...
... synthesis pathway. Glucose metabo-
lism in the CNS en route to fatty acids gives rise to
ATP and NADH, and inhibits isocitrate dehydroge-
nase, thereby increasing the level of citrate which is ... evidence
supports this view. First, hypopthalamic malonyl-CoA
is suppressed during fasting and increases upon refeed-
ing [13,19]. This is not true for other areas of the brain
suc...
... itself is pro-
tected, but L8 is not. For the P9 subdomains, most of
P9 is protected, but most of P9.1 is neutral. The
5¢ strand of P9.0 is protected despite the absence of
the 3¢ strand. For the ... [pre-RNA–nMg
2+
]
active
term is the concentration of
active ribozyme, and [pre-RNA]
total
is the RNA concentra-
tion. K
Mg
2+
and K
Mn
2+
are the apparent disso...
... proteolysis of MurA [15]. Here we report the thermo-
dynamic profile of UDPNAG binding to two MurA single
mutants, K22V and R120K, and the double mutant K22V/
R120K. The emphasis is put on analysis ... 1UAE [11]), conformation. The
thiol group of C115 is highlighted in green and
the nitrogen atoms of R120 and K22 in blue.
The open form of MurA is unliganded (A) and...
... by the
programming language Modula-2 on the one hand and
by the notion projection from X-theory on the other
hand.
The second problem was that there is no way of
explicitly controlling the ... that
the place of this subdivision coincides with the 'switch
point'. There is another argument for making this sub-
division: the first part of the control exp...
... in vivo is essential for the full
understanding of these mechanisms, and spectroscopic
analyses in living cells will greatly aid the detailed
analysis of the processes involved in these diseases. ... expansion of the polyQ repeat in the AR is
responsible for spinal and bulbar muscular atrophy.
The expanded polyQ tract is encoded by a CAG repeat
in the causative genes,...
... it is possible that stop codon specificity
is regulated by the conformation of this flexible part
of the C-domain. His334, His366 and Glu370 are
located outside this loop, and this may explain the
absence ... with the
HN proton of the His356 imidazole ring, either
directly or through a water molecule. His356 is near
Asp353 in the open conformer and near Glu365 and
Glu3...