... interruption of the geometry
of the recognition helix for either Antp or the TTF-1
HD, the anomalous amide exchange pattern and the
NOE connectivity data of the C-terminal portion of
helix III ... inferred from the
NOE data, have little effect on the value of the Æs
mi
æ
estimate, and adds confidence to the assumption of
isotropic motion adopted by the e...
... designing the truncated Rep245 protein
containing the residues predicted to be responsible for
polymerase and primase catalysis, and reported on the
functional characterization of the main functions of
this ... DNA
recognition and binding and is positioned left of
the active site [14].
Rep245 is both capable of de novo synthesis of
DNA primers and of elongati...
... sequence and sequence alignment of Cyn d 24. (A) Nucleotide and deduced amino acid sequences of Cyn d 24. The numbers
on the right of the figure indicate the positions of the nucleotide sequence. The ... Promo-
tion of Research-oriented university program from the
Ministry of Education and Grant NSC 92–2320-B-002-
174 from the National Science Council, Taiwa...
... PKIb contained only small amounts of
a-helix and b-structures, but large amounts of random coil
and turn structures, which may explain its high thermosta-
bility. The details of its conformational ... are
specific and potent inhibitors of the C subunit; however,
unlike the R subunit, PKI inhibition of the C subunit is not
relieved by cAMP [3–5]. Moreover, the PKIs als...
... formed by the well-
converged parts of XPCB–hHR23B. However, because
of secondary effects from the divergent positioning of
the flexible N-terminal region (275–283), the boundary
and size of HT1 ... conserved among the STI1 homologs are marked in blue, and the Pro residues not conserved among the STI1 homologs are marked
in cyan. (B) Ribbon presentation of the XPC...
... splicing
variant of the b
1
subunit, rat b
1A
[7], have been cloned and
characterized.
The rat b
1A
subunit is a splicing variant of the b
1
subunit via intron retention. The N-terminal half of the
b
1A
subunit ... the part of
intron 3 adjacent to exon 3 (Fig. 1C and Table 1). As the
site of divergence between the b
1
and b
1B
subunit cDNAs
was located precisel...
... analysis of the A. gambiae 3-HKT. The full length sequence of the isolated Ag-hkt cDNA clone: the putative translation start
codon and stop codon are shown in bold. The primary sequence of the conceptual ... concentrations of the
molecule to the reaction samples containing 5 mmd,l-3HK
as the amino donor. The amount of XA produced after a
5-min incubation was me...
... concentration on the velocity of the two
arogenate dehydrogenases TyrAAT1 (upper panels), and TyrAAT2
(lower panels). (A) and (C) Plots of the velocity as a function of
increasing concentrations ... required for understanding the partition
of the carbon flux between the different end products. The
present study is the first to report the purification and
detaile...
... mouse and
human exhibit relatively few differences in the size of
their respective introns. Furthermore, there is a strong
conservation of exon organization. The exon size and
the intronic positions ... organization of the Cc RNase gene and its derived
mRNA isoforms. The rectangles represent the exons and the horizon-
tal bold lines the introns. The black parts...
... versus the concentration of the activation domain and the
curves show the best fit of the data to the quadratic Eqn (1).
Table 3 lists the calculated dissociation constants for the wild-type
and ... a2–a4
connect the strands b1 and b2, whereas helices a5–a7
follow strand b5. The long helix a6 is surrounded by the
central b sheet on one side, b6–b7 and the...