báo cáo khoa học: " The 1000 Genomes Project: new opportunities for research and social challenges" pptx

... discrimination on the basis of the results of genetic testing.© 2010 BioMed Central Ltd The 1000 Genomes Project: new opportunities for research and social challengesMarc Via*, Christopher Gignoux and ... records. Rather, the decision on whether to legislate the use of genetic test results has been left to the discretion of each individual country.Conclusionse information that the 1000 Genomes ... projects before public beneﬁts from these new technologies are developed. e attention from the media will probably increase the public’s expectations of the 1000 Genomes Project and its potential...

Báo cáo khoa học: "The Human Language Project: Building a Universal Corpus of the World’s Languages" pptx

... code(s), and data type. This informationcan itself be curated and stored in the form of anOLAC archive, to permit search over the union of the existing and newly documented items. Workalong these ... recorders and net-books, project-speciﬁc software for transcription and sentence-aligned translation, network band-width for upload to the repository, and suitabletraining and support throughout the ... the manystrands of activity described here, as theircontribution to the global effort to docu-ment the world’s linguistic heritage beforemore languages fall silent.1 Introduction The grand...

Báo cáo y học: "The 1001 Genomes Project for Arabidopsis thaliana" pptx

... manner similar to the A. thaliana project, onprevious HapMap information, but because of the greatercomplexity and repetitiveness of human genomes, much of the initial effort for the human project ... proposal with the 1000 Genomes effort for humans [37] and the Drosophila GeneticReference Panel projects [38]. Because A. thaliana acces-sions are inbred with effectively constant genomes, and canbe ... split efforts between wild accessions and the intercrossed lines.This leaves the question: why 1,001 genomes, and not 101 or10,001? As with the human 1000 Genomes project, 1,001 isobviously...

Báo cáo khoa học: "The utility of parse-derived features for automatic discourse segmentation" doc

... in the RST-DT donot correspond to a well-formed subtree in the hu-man annotated discourse parse for that document.Therefore, to perform accurate and efficient pars-ing of the RST-DT at the ... categories as PP and VP lose their argu-ments in the shallow parse.As a practical matter, we limit the number of cat-egories in the flat production to 8 to the left and 8 to the right of the boundary. ... returns the value 1 whenc = E and the current word is the , and returns0 otherwise. Given a d-dimensional parameter vec-tor φ, the output of the classifier is that class whichmaximizes the dot...

Báo cáo khoa học: The oxidative effect of bacterial lipopolysaccharide on native and cross-linked human hemoglobin as a function of the structure of the lipopolysaccharide A comparison of the effects of smooth and rough lipopolysaccharide ppt

... Atequilibrium, the concentration of deoxyHb is much greaterin the low afﬁnity cross-linked Hb. Therefore, anotherdifference between cross-linked Hb and Hb A0may be in the binding of the deoxyHb to the ... comparison of the effects of roughandsmoothLPSsofE. coli, both in the presence and absence of EDTA (Fig. 1). The rate of oxidation wasincreased in the presence of the LPSs of both the smooth and rough ... effect on the oxidation rate of cross-linked Hb in the presence of LPS wasnegligible for both the smooth and rough LPSs (Fig. 1). The effect of the LPSs of smooth and rough S. minnesotaon the oxidation...

Báo cáo khoa học: The human cytomegalovirus-encoded chemokine receptor US28 induces caspase-dependent apoptosis pptx

... previously been shown toblock the interaction between these ligands and theirreceptors, and ligand-mediated cell death. Treatmentof US28-tranfected 293T cells with the decoy receptorsCD95-Fc, ... 7-Valorization, and Fondation pour la Recherche Me´dicale (FRM) (JCA), and postdoctoral fellowships from SIDACTION and ANRS (OP) and Vrije University talent programme(PC), and by the Royal Netherlands ... Zanzami for helful discussion, and J. Abrams,W. Behring, C., S. Korsmeyer, R. LaFemina, and B. Rodgers for generous gift of reagents. We alsogreatly thank H. Coleman, and J. Sinclair for theirpersonal...

Báo cáo khoa học: "The Treegram Index An Efficient Technique for Retrieval in Linguistic Treebanks" docx

... those available for the tree database. (2) VENONA collects q's treegrams and represents them by sets of treegram parts. For a given query treegram, VENONA expands the structure ... the first h lev- els of the subtree rooted in v. This ap- proach keeps the index small but intro- duces another problem: A query treegram may not appear in the treegram index as it is. Therefore, ... matching treegrams for that subtree. (c) It is quite expensive to intersect the tree sets T(DB, g) for all treegrams g contained in the query q. VENONA addresses these problems by the following...

Báo cáo khoa học: The intrinsic structure of glucose transporter isoforms Glut1 and Glut3 regulates their differential distribution to detergent-resistant membrane domains in nonpolarized mammalian cells potx

... process through these FLAG-tagged proteins.Neither the N-terminus nor the C-terminusof Glut1 is needed for the DRM distributionTo determine the functional domains responsible for the DRM distribution ... case, the distribution of endogenous Glut1 wasunaffected. The N-terminal membrane-spanning regionsof Glut1 are needed for the DRM distributionTo further deﬁne the domains responsible for the DRM ... delivers proteins and lipids to the cor-rect membrane domains during cell growth [29]. The best characterized system comprises polarized epithelialcells, and the sorting machinery for membrane proteinsthat...

Báo cáo khoa học: The N-glycans of yellow jacket venom hyaluronidases and the protein sequence of its major isoform in Vespula vulgaris pdf

... majorpolypeptide in the 43 kDa band of V. vulgaris as a new isoform of hyaluronidase. Furthermore, we ana-lyzed the hyaluronidase band in ﬁve other commonyellow jacket species and we investigated the N-glycanstructures ... stand highon the list of organisms whose genomes will be fullysequenced in the near future, the composition of the 43 kDa band would not have been revealed otherwise.Cloning of the two isoforms ... cloning of the cDNA of the newly discovered hyaluronidase isoform (referredto as Ves v 2b in the present article, in contrast to the known form, Ves v 2), the N-terminal sequence and internal...

Báo cáo khoa học: "The Prevalence of Descriptive Referring Expressions in News and Narrative" potx

... communicating information about the ref-erents. This descriptive information is sometimes new, sometimes necessary for understanding the text, and sometimes just for added ﬂavor. Butwhen the expression ... properly identify the referentsof each expression. But the real text, the openinglines to the folktale The Beauty and the Beast, isactually much more lyrical:Once upon a time there wasa rich ... daughters. They lived inavery ﬁne house and their gowns were madeof the richest fabric sewn with jewels.All the boldfaced portions – namely, the choiceof head nouns, the addition of adjectives, the...

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