... physicians. In response to its chronic
deficiency of medical access, the province introduced a
state-sponsored healthcare system to provide care for its
citizens. Other provinces with inadequate medical ... Morone
[5]. Their fine book demonstrates that all of the proposals
emanating from the gaseous environment on Capital Hill
have been considered over and over again...
... ‘anemia of
inflammation’ induced by excessive hepcidin synthesis in
the liver and resultant inactivation of ferriportin. The latter
diminishes iron transport from the gut lumen and the
macrophage ... etiology of
both CD and UC is that they are the result of very
Musings
Musings on genome medicine: Crohn’s disease
David G Nathan and Stuart H Orkin
Address: Dana-...
... S: My Life in Science. London: BioMed Central; 2001.
2. Nathan DG, Orkin SH: Musings on genome medicine: gene
therapy. Genome Med 2009, 1:38.
3. Johnson FL, Thomas ED: Treatment of relapsed ... and the consequent accumulation of heparan
sulfate and dermatan sulfate throughout the body. The
disorder is caused by mutations in alpha-l-iduronidase,
but the various m...
... interferon alfa further increased the
response rate [9]. But the treatment remains difficult,
with side-effects that resemble the cytokine-releasing
consequences of cancer chemotherapy, and the ... Orkin Genome Medicine 2010, 2:4
http://genomemedicine.com/content/2/1/4
doi:10.1186/gm125
Cite this article as: Nathan DG, Orkin SH: Musings on genome medicine:
Hepatitis C....
... containing the
black stripes. Injection of 20 pmol of GBP enhanced
the expression of both enzymes in the dorsal integu-
ment containing the black stripes only (Fig. 6C), indi-
cating that GBP must increase ... GBP
strongly induces Ca
2+
in ux into brain synaptosomes
[20], we examined whether incubation of the dorsal
integument with GBP enhanced the expression levels
of...
... that they con-
tain only a few genes not involved in transcription or
translation, none of which are related to photosynthesis.
However, none of the remaining non-transcriptional/
translational ... in the
LSC region, the other in the SSC encompassing only two
genes, ccsA and trnL-UAG. Both of these inversions border
on regions that once contained ndh genes. Extensive non...
... function of TRAIL containing
the extracellular domain (amino acids 114–281) of the
human liver cancer cell line, QGY-7703 [27], we treated the
cells with increasing concentrations of TRAIL and then
analysed ... synergistic effect involves the upregulation of
Bax and tBid, but not of DR4 or DR5. The interaction
between Bax and tBid results in the amplification of
mito...
... MALDI-PSD-TOF MS
(data not shown). As these ions only contained one
Fuc3NAc residue each, these experiments could not
provide any information concerning the Fuc3NAc distri-
bution on the Rha backbone. These ... 2). The anomeric
1
J
C,H
-value (161 Hz) indicated the b
configuration. A further indication of the b configuration
was the observation of a coupling constant H1 to H2,...
...
S= .3ZI.T;,
then
with
solutions
In
practice,
B
and
B-’
may
be
difficult
to
construct
depending
on
the
definition
of
S.
In
such
cases,
the
alternative
equations
(3.2)
may ...
exemple
est
donné
qui
illustre
ces
consid.,rations.
Mots-clés :
Prédiction
linéaire,
vecteurs
corrélés.
I.
Introduction
In
mixed
linear
models,
the
covariances
among...
... from the National Program of High
Technology Development of China, the National Program on the Develop-
ment of Basic Research in China, and the National Natural Science Founda-
tion of China.
References
1. ... determine the putative transcriptional regulation mechanism of OsWRKY13, the
putative cis-acting elements of OsWRKY13-influenced genes were analyzed using...