... Mode of administration Status CompanyAge-related macular degeneration (AMD) Topical Phase II AllerganRespiratory syncytial virus (RSV) Local/direct Phase II AlnylamLiver cancer (HCC and others) ... fromcapped, polyadenylated transcripts that can also function as mRNAs.RNA 2004, 10:1957-1966.45. Chung KH, Hart CC, Al Bassam S, Avery A, Taylor J, Patel PD, et al:Polycistronic RNA polymerase ... RNAi substrates and aremore amenable to Pol-II transcription and may seem tobe more attractive for therapies [44,45]. But to dateshRNA- and artificial miRNA-based strategies have beencompared...