... therapies such as rituximab, an anti-CD20 antibody[2], and the increased interest in the role of autoantibodies in RA. In addition to producing antibodies, proinflammatorycytokines and chemokines, B ... Suematsu A, Okamoto K, Yamaguchi A, Morishita Y, Kadono Y, Tanaka S, Kodama T, Akira S, Iwakura Y, Cua DJ,Takayanagi H: Th17 functions as an osteoclastogenic helper Tcell subset that links T cell activation ... [112].ConclusionsOver the past couple of years advances have been made in the understanding of the involvement of T cells in the immunopathology of autoimmune diseases, with a focus onproinflammatory cytokine...