Báo cáo y học: "Protein Never in Mitosis Gene A Interacting-1 regulates calpain activity and the degradation of cyclooxygenase-2 in endothelial cells" pot
Báo cáo y học: "Protein Never in Mitosis Gene A Interacting-1 regulates calpain activity and the degradation of cyclooxygenase-2 in endothelial cells" pot
... that PIN1 may normallyfunction to maintain calpain activity and, consequently,restrain the induction COX-2, iNOS, and perhaps othersubstrates in MAEC. PIN1 is likely to regulate a range of calpain- dependent ... slowed the degradation of COX-2 in MAEC, an effectrecapitulated by an inhibitor of calpain. Given the sensitivity of COX-2 and iNOS to calpain, PIN1 may normallylimit induction of these and other ... 9(page number not for citation purposes)Journal of InflammationOpen AccessResearchProtein Never in Mitosis Gene A Interacting-1 regulates calpain activity and the degradation of cyclooxygenase-2...
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Báo cáo y học: "Human T-cell leukemia virus type I (HTLV-I) infection and the onset of adult T-cell leukemia (ATL)" pps
... 126:81-84.105. Yoshie O, Fujisawa R, Nakayama T, Harasawa H, Tago H, Izawa D,Hieshima K, Tatsumi Y, Matsushima K, Hasegawa H, Kanamaru A, Kamihira S, Yamada Y: Frequent expression of CCR4 in adult T-cell ... I tax. Int J Cancer 2005.24. Yamaoka S, Inoue H, Sakurai M, Sugiyama T, Hazama M, Yamada T,Hatanaka M: Constitutive activation of NF-kappa B is essentialfor transformation of rat fibroblasts ... leukemia. Blood 2001, 97:987-993.65. Takeda S, Maeda M, Morikawa S, Taniguchi Y, Yasunaga J, Nosaka K,Tanaka Y, Matsuoka M: Genetic and epigenetic inactivation of tax gene in adult T-cell leukemia...
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Báo cáo y học: "Increased interleukin-17 production via a phosphoinositide 3-kinase/Akt and nuclear factor κB-dependent pathway in patients with rheumatoid arthritis" ppt
... ACCTGG AAA TAC CCA AAA TTC-3') were generated by 5'-end labeling of the sense strand with [γ-32P]dATP (Amer-sham Pharmacia) and T4 polynucleotide kinase (TaKaRa).Unincorporated nucleotides ... proinflam-matory properties [5,22]. RA is characterized by hyperpla-sia of synovial lining cells and an intense infiltration bymononuclear cells [23]. Proinflammatory cytokines such asIL-1 and ... min. In contrast, non-phosphorylated Akt and β-actin remained unchanged regardless of incubation time.PHA, concanavalin A and IL-15 also demonstrated the same effect on phosphorylated Akt as...
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Báo cáo y học: "Dynamic compression counteracts IL-1β induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs" pdf
... and revealed efficiency values presented in table 1.Data normalization and statistical analysesFluorescence data was collected during the annealing stage of amplification and data was analyzed ... pairs)EfficiencyiNOS U14640 Probe: 5'-FAM-CGCGATCCCTGCTTGGTGGCGAAGATGAGCGATCGCG-DABCYL-3' Forward: 5'-GTAACAAAGGAGATAGAAACAACAGG-3' Reverse: 5'-CAGCTCCGGGCGTCAAAG-3'81 ... 88:135-141.51. Saklatvala J: Inflammatory signalling in cartilage. MAPK and NF-κB pathways in chondrocytes and the use of inhibitors forresearch into pathogenesis and therapy of OA. Curr DrugTargets 2007,...
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Báo cáo y học: "Small interfering RNA mediated Poly (ADP-ribose) Polymerase-1 inhibition upregulates the heat shock response in a murine fibroblast cell line" pptx
... protein-proteininteraction and catalytic activity of the PARP proteinplay a key role in modulation of the heat shockresponse.AcknowledgementsFunding for this study was provided by the National Institutes ... Salzman AL, Szabo C: Peroxynitrite-mediated DNA strand breakage activates poly-adenosine diphosphateribosyl synthetase and causes cellular energy depletion in macrophagesstimulated with bacterial ... units has an adeninemoiety c apable of base stacking and hydrogen bonding,along with two phosphate groups that carry negativecharges. These polymers cause profound changes in the structure and...
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Báo cáo y học: " Small interfering RNA mediated Poly (ADP-ribose) Polymerase-1 inhibition upregulates the heat shock response in a murine fibroblast cell line." pptx
... Veres B, Gallyas F Jr, Varbiro G, et al: Decrease of the inflammatoryresponse and induction of the Akt/protein kinase B pathway by poly-(ADP-ribose) polymerase 1 inhibitor in endotoxin-induced ... conceived the study. RA, RLD participated in the design of the study. Allauthors read and approved the final manuscript.Competing interests The authors declare that they have no competing interests.Received: ... results indica te that PARP-1 servesas a repressing factor of the heat shock response by reg-ulating the expression of HSP-70. Both protein-proteininteraction and catalytic activity of the PARP...
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Báo cáo y học: " Body mass index is associated with reduced exhaled nitric oxide and higher exhaled 8-isoprostanes in asthmatics" docx
... A, Sumida Y, Gabazza EC, Murashima S, MoriokaK, Maruyama N, Kitagawa N, Tanaka T, Hori Y, Nakatani K, Yano Y, Adachi Y: Oxidative stress is associated with adiposity and Respiratory Research 2007, ... airway changes in airway NO and airway oxidative stress. Overall, these find-Association of the ratio of serum leptin and serum adiponectin with the log of exhaled NO in subjects with asthma ... severity in asthmatics are unknown.Recent experimental data suggest that obesity-relatedchanges in adipokines could play a critical role in mediat-ing airway inflammation and bronchial hyperresponsive-ness...
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Báo cáo y học: " Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment" pot
... 1Y6 , Canada, 2Second Department of Internal medicine, Nagasaki University School of Medicine, Nagasaki, Japan and 3Environmental Health Directorate, Health Canada, Ottawa, Ontario, CanadaEmail: ... PM10(EHC-93)-induced interaction of human AM and bronchial epithelial cells (HBEC)enhances the synthesis and release of a variety of pro-inflammatory cytokines and that supernatants from theseco-cultures instilled ... pro-inflamma-tory cytokines that induce airway inflammation and con-tribute to the airway lesions in asthma and chronicobstructive pulmonary diseases [9]. In vitro, AM and lungepithelial cells...
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Báo cáo y học: "SIV antigen immunization induces transient antigen-specific T cell responses and selectively activates viral replication in draining lymph nodes in retroviral suppressed rhesus macaques" pptx
... GuidefortheCareandUseofLaboratory Animals” prepared by the National ResearchCouncil. The studies were approved by the University of Pennsylvania and Tulane Institutional Animal Care and Use ... 3,5, and 7) and la te (days 9, 1 1, and 14) time points asgroups. Comparing viral replication in all animalsinduced by gag and pp65 immunization in drainingLNMCs at t he early time point (days ... TTGCAGCACCCACAACCA-3’Reverse: 5’-TGATCCTGACGGCTCCCTAA-3’Probe: 5’- CTCCACAACAAGGACA-3’IFN-g Forward: 5’- GTGTGGAGACCATCAAGGAAGAC-3’Reverse: 5’- CGACAGTTCAGCCATCACTTGGAT-3’Probe: 5’-ACTGACTCGAATGTCCAACGCAAAGC-3’GAPDH...
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Báo cáo y học: " Formulas Pro/con debate: Is intensive insulin therapy targeting tight blood glucose control of benefit in critically ill patient" doc
... [21,23], although some of the trials havebeen small [21]. As in many areas of intensive care practice, the choice of a target range for blood glucose is a matter of balancing potential benefit against ... morbidity and mortality as well as the characteristics of the individual ICU, such as availability of staff and laboratory equipment [39]. Until the balance of risks and benefits is better defined, ... did not reach the traditionally accepted level of statistical significance in the intention-to-treat analysis. The intention-to-treat analysis is always the most relevant resultfor any randomized...
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Từ khóa: Báo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018chuyên đề điện xoay chiều theo dạngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngTìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXChuong 2 nhận dạng rui roTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtMÔN TRUYỀN THÔNG MARKETING TÍCH HỢP