... activated in adipose tissue in obesity [12,13], the
induction of SLPI in adipose tissue during obesity may be
influenced by the activation state of the TLRs. Higher
expression of SLPI in the visceral ... Adapala et al.: Novel anti-inflammatory role of SLPI
in adipose tissue and its regulation by high fat diet. Journal of
Inflammation 2...
... insulin
resistance, induction of SLPI locally in adipose may also
play a role in the prevention of inflammation-induced
insulin resistance. In summary, we have demonstrated
that obesity is accompanied by increased ... Adapala et al.: Novel anti-inflammatory role of SLPI
in adipose tissue and its regulation by high fat diet. Journal of
Inflammati...
... gain during antipsycho tic drug
therapy [15].
An understanding of the role of appetite changes in
weight gain during antipsychotic treatment would be
helpful to clinicians and patients, some of ... Study 2); Eating Inventory (EI, Study 3) [20];
Food Craving Inventory (FCI, Study 3) [21]; and Ea ting
Attitude Scale (EAS, a Lilly-developed scale, assessing
appetite and eating be...
... co-immunoprecipitated
only the phosphorylated form of RNAP II from HTLV-I
infected cells. Thus, if only indirectly, Tax may increase
kinase activity resulting in enhanced CTD phosphoryla-
tion for steps following initiation, ... resulting in the loss
of the capping machinery and the association of splicing,
elongation and chromatin remodeling factors. In the case
of HTLV-I,...
... identifying the role
played by trans-acting factors in pseudoexon inclusion.
However, because of its significance, this is an area of
research that would probably benefit from increased
attention by ... Nishino I, Goto Y, Miike T & Nonaka I
(1999) Newly recognized exons induced by a splicing
abnormality from an intronic mutation of the dystro-
phin gene resulting in Duc...
... Matsushima Y, Kobayashi Y, Yamamoto T: Age estima-
tion by measuring the racemization of aspartic acid from total
amino acid content of several types of bone and rib cartilage:
a preliminary account. ... authors of that study further found that the hyaluronan-
binding (G1) domain of aggrecan is retained early in the dis-
ease process and then finally released to synovial f...
... adjudication of the reason for withdrawal.
In summary, the study by Saad and colleagues gives us
important insights into daily-life use of TNF inhibitors in PsA, a
disease that too often is secondary to ... reason of ineffectiveness
and terminated for the reason of toxicity. This was done by
censoring patients with treatment terminations other than the
reason of interest...
... were
residues Gly261 and Gly262. The replacement of Gly262 by
Ala resulted in an inactive enzyme. Substitution of Gly261
by Ala resulted to an enzyme with lower stability and
increased energy of activation. ... Bouriotis
1,2
1
Department of Biology, Division of Applied Biology and Biotechnology, University of Crete, Greece;
2
Institute of Molecular Biology
and Biot...
... presence of membrane-bound gp130 proteins by
flow cytometry.
COS7 cells were transiently transfected using the Fugene
method. Efficiency of transfection was analysed by flow
cytometry.
Flow cytometry
Cells ... Deletion
of a single domain in the membrane-proximal part of gp130
leads to a shift of the receptor areas involved in ligand
binding closer to the membrane, resulting in...