báo cáo khoa học: " Adoption and sustainability of decision support for patients facing health decisions: an implementation case study in nursing" docx

... purposes) Implementation ScienceOpen AccessResearch article Adoption and sustainability of decision support for patients facing health decisions: an implementation case study in nursingDawn ... Canadian Institutes of Health Research (CIHR) Group Grant on Decision Support Tools for Clinicians and Patients, and Dr. Stacey received a doc-toral studies award from the Ontario Ministry of ... the absence of Canadianguidelines, performance indicators were based on Ameri-can standards [21]. However, funding for healthcare in the US is organized differently than it is in Canada, withreimbursement...

Báo cáo khoa học: "Development and evaluation of indirect ELISA for the detection of antibodies against Japanese encephalitis virus in swine" pptx

... ...

Báo cáo khoa học: "Simulation and comparison of silvicultural alternatives for even-aged Pinus pinaster Ait stands in Galicia (Northwestern Spain)" pps

... describing the medium and long-term develop-ment of a forest stand, silvicultural planning ensurescontinuity of forest management. For even-aged com-mercial stands of maritime pine (Pinus pinaster ... Pinus pinaster Ait. en Galicia. Premio ENCE deInvestigación Forestal, 1992 (unpublished).[17] Miina J., Optimizing thinning and rotation in a stand of Pinus sylvestris on a drained peatland ... wasdeclining since more intensive silvicultural conceptswere introduced in Northwestern Spain as a result of increasing harvesting costs and stagnating pulpwoodprices. Nowadays, maritime pine stands...

Tài liệu Báo cáo khoa học: Structure and function of active chromatin and DNase I hypersensitive sites pdf

... Constanze Bonifer for her helpful advice and comments on the manuscript, and Karolin Luger and Jacques Cote for informative discussions. I thank Gra-ham Goodwin for giving me a good initiation into ... these advanceshave been accompanied by a relative decrease in thenumber of studies aimed at gaining an understanding of the structural conformation of chromatin, and thechanges in chromatin structure ... transcribedregions of active genes in human T cells [124]. In a study in yeast, mutations were introduced alone or in combination in lysines 5, 8, 12 and 16 in the gene for histone H4 [125]. Of...

Tài liệu Báo cáo khoa học: miRNAs and regulation of cell signaling pptx

... repressingthe indicated targets and presumably hundreds of other as yetunidentiﬁed targets. (B) miR-34a and the miR-34a-binding site in the 3¢ UTR of genes shown in (A).miRNAs and cell signaling ... post-transcriptionally bybinding to target mRNAs in a sequence-speciﬁc manner. A large number of genes appear to be the target of miRNAs, and an essential role for miRNAs in the regulation of various ... MEK1expression, and leads to the repression of cell prolifera-tion during megakaryocytic differentiation in K562cells [21]. In addition, miR-34c is induced under thecontrol of both p53 and p38-MAPK, and...

Tài liệu Báo cáo khoa học: Expression and secretion of interleukin-1b, tumour necrosis factor-a and interleukin-10 by hypoxia- and serum-deprivation-stimulated mesenchymal stem cells Implications for their paracrine roles ppt

... Piwashes and incubation withthe nuclear stain 4¢,6-diamidino-2-phenylindone for 20 min,the MSCs were washed in NaCl ⁄ Pi for 10 min and mounted in gelvatol for microscopic imaging.Protein extraction ... presence and absence of IL-10. *P < 0.05 and **P < 0.01 versus Cont group. (D) Representativewestern blots for collagen I and III in the presence and absence of 0.1 lM angiotensin II and IL-10.Paracrine ... stimulatorysignal in order to secrete IL-1b and TNF-a.Hypoxia⁄SD induces the transcription and secretion of IL-10Because of the lack of secretion of the in ammatorycytokines IL-1b and TNF-a from...

Tài liệu Báo cáo khoa học: Investigation and prediction of the severity of p53 mutants using parameters from structural calculations pptx

... mutations and NOXA and p53R2 slightly less so. This is indicated by the averageactivity of mutants in the central domain of 26% for WAF1 and 34% for MDM2, 71% for NOXA and 61% for p53R2, and around ... which are the true driving force for cell transfor-mation [3].Passenger mutations can be found in coding or non-coding regions of any gene, and distinguishing themfrom driving mutations is a ... involved in DNA binding and 244 and 246are in very close proximity to DNA binding. This indi-cates that p53R2 either does not use these residues for binding or that they are not necessary for...

Tài liệu Báo cáo khoa học: Isolation and characterization of four type 2 ribosome inactivating pulchellin isoforms from Abrus pulchellus seeds docx

... and IV and refers to each pulchellinisoform (P I, P II, P II and P IV). The A-chain of P IIwas formerly cloned and named recombinant pulchel-lin A-chain [15]. The heterologous expression and refolding ... the animal that showed the high-est hemagglutination titer for each isoform, humanerythrocytes for P I and P II, and rabbit for P III and IV.The plates were incubated for another 30 min at ... suboptimal binding of GalNAc in one or bothbinding pockets of P I. However, in striking contrastwith the rescue of protein synthesis observed for P I and P II, protection against P III and P IV...

Tài liệu Báo cáo khoa học: Expression and function of Noxo1c, an alternative splicing form of the NADPH oxidase organizer 1 doc

... Nox1-expressing and Noxa1-expressing human cancer cell lines [the androgen-independent prostate cancer LNCaP cells, and theandrogen-independent prostate cancer PC3 and DU145 cells (Fig. 2)], indicating ... (PX)domain in the N-terminus. PX domains occur in avariety of proteins involved in cell signaling, mem-brane trafficking, and polarity establishment, and func-tion as phosphoinositide-binding modules ... extent of membranelocalization of Noxo1b and Noxo1c. Theintensities of immunoreactive bands for HA-Noxo1b and HA-Noxo1c in (B) werequantified using a LAS-1000plus (Fuji film)image analyzer and...

Tài liệu Báo cáo khoa học: Production and characterization of a secreted, C-terminally processed tyrosinase from the ﬁlamentous fungus Trichoderma reesei ppt

... Westerholm-Parvinen1, Nisse Kalkkinen2,Johanna Buchert1 and Kristiina Kruus11 VTT Technical Research Centre of Finland, Espoo, Finland2 Protein Chemistry Research Group and Core Facility, Institute ... reactions in themultistep biosynthesis of melanin pigments, beingresponsible, for instance, for skin and hair pigmenta-tion [4]. Tyrosinases play an important role in regula-tion of the oxidation–reduction ... performed using aQ-TOF instrument (Micromass Ltd, Manchester, UK).Protein and peptide sequencingN-terminal protein and peptide sequencing was performedusing a Procise 494A Sequencer (Perkin Elmer,...

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