... 6-OHDA are mainly attrib-uted to the formation of free radicals, inflammatory pro-cesses and apoptosis [1,2].Early studies indicated that NO participated in cellularsignaling pathways regulating ... pathway may be involved.Background A hydroxylated analogue of dopamine, namely 6-Hydro-xydopamine (6-OHDA) which induces damage of dopa-minergic neurons in vivo and in vitro, is commonly used in ... buergerianum (Gujingcao), an aquatic plantnative to Mainland China (eg Zhejiang, Guangdong and Fujian provinces), Taiwan and Japan, is used in Chinese* Correspondence: SimonLee@umac.mo1State Key...