... immuno-inflammatory system with the aetiology and the pathophysiology of MDD.Recently, a larger panel of pro- a nd anti-inflammatorycytokines was measured in a case/ control population ofMDD showing ... the onset of antidepressants’ action as yet and treatment efficacy is only determined by clinicalmeasures and in the later course of treatment. Currentlyavailable data can not answer the question, ... Centre, Mainz, Germany.3Clinic for Psychiatry and Psychotherapy,Katzenelnbogen, Germany.4Clinic for Psychiatry and Psychotherapy, Dr.Horst-Schmidt-Kliniken, Wiesbaden, Germany.Authors’...