... Italy, Israel, Portugal, and Spain; NorthAmerica: Canada, and the United States; South America:Brazil, an d Uruguay; Asia: China, Indonesia , Japan, andSingapore; and Australia.Cost analysisAll ... Mehta RL, McDonald B, Gabbai FB, Pahl M, Pascual MT, Farkas A, Kaplan RM,Collaborative Group for Treatment of ARF in the ICU: A randomizedclinical trial of continuous versus intermittent dialysis ... cost of anticoagulation is an important part of the total cost of RRT: nearly 50% of RRT patients(42.03%) in Japan were treated with nafamostat mesy-late, a synthetic serine protease inhibitor...