... and bindsto DNA as a heterodimer usually composed of USF1 and USF2. USF has been implicated in the r egulation of m anygenes and normally acts as a transcriptional activator.However, it has ... Francastel, C., Cimora, D.M., Reik, A. , Martin,D.I.K. & Groudine, M. (2000) Nuclear localization and histone acetylation: a pathway for chromatin opening and transcriptional activation of ... direct contact and thattranscription complexes and chromatin-modifying activit-ies are transferred b y a looping mechanism. On the otherhand, the observation that a certain fraction of adult cellscoexpress...