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Diagnosis and Management of Pituitary Disorders - part 8 ppt

Diagnosis and Management of Pituitary Disorders - part 8 ppt

Diagnosis and Management of Pituitary Disorders - part 8 ppt

... and Intermittent Treatment -3 0 -2 5 -2 0 -1 5 -1 0 -5 004wk 8 wk12wk16wk20wk24wk 28 wk 32wk36wklb.PlaceboQ O Mo. ContinuedMunro JF et al. Br Med J 19 68 Feb 10;1(5 588 ):352 -4 Fig. 3. Intermittent ... National Institute of Child Health and Human Development(NICHD) conference, the diagnosis of PCOS requires 1) oligo- or anovulation and 2) biochemical and/ or clinicalsigns of hyperandrogenism, such ... Nuclear Factor-B(NF-B) transcription factor, driving hepatocyte synthesis of TNF and IL-6 (27, 28) . Recent studies in transgenicmice with hepatocyte-specific overexpression of IKK-beta demonstrate...
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Diagnosis and Management of Pituitary Disorders - part 1 potx

Diagnosis and Management of Pituitary Disorders - part 1 potx

... Science UniversityBeaverton, ORISBN: 97 8- 1 - 588 2 9-7 9 4-5 e-ISBN: 97 8- 1 -6 032 7-0 4 3-4 Library of Congress Control Number: 20 089 23501©20 08 Humana Press, a part of Springer Science+Business Media, LLCAll ... human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells.Proc Natl Acad Sci1 987 ;84 : 388 1– 388 5. 82 . Cooper GJ, ... Sim RB, Reid KB. Purification and characterization of a peptide from amyloid-richpancreases of type 2 diabetic patients. Proc Natl Acad Sci 1 987 ;84 :86 28 86 32. 83 . Janson J, Soeller WC, Roche...
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Diagnosis and Management of Pituitary Disorders - part 2 docx

Diagnosis and Management of Pituitary Disorders - part 2 docx

... dysfunction, and beta-cell failure? Atherosclerosis2000;1 48: 17–21.2 08. Corbett JA, Lancaster JR, Jr., Sweetland MA, McDaniel ML. Interleukin-1 beta-induced formation of EPR-detectable iron-nitrosylcomplexes ... liver and muscle insulin resistance and diabetes (8) . In addition, both high-fatfeeding and IKK- overexpression increase expression of proinflammatory cytokines such as IL-6, IL-1, and TNF ... lipotoxicity and insulin secretion. Diabetologia 1999;42:1 28 1 38. 28. Sako Y, Grill VE. A 4 8- hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and B cell...
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Diagnosis and Management of Pituitary Disorders - part 3 docx

Diagnosis and Management of Pituitary Disorders - part 3 docx

... and the development of diabetes. JAMA 2001; 286 : 188 2– 188 5.44. Bosch J, Yusuf S, Gerstein HC, et al. Effect of ramipril on the incidence of diabetes. N Engl J Med 2006;355:1551–1562.45. Dahlof ... DM Sanders L, Huang J. Efficacy and safety of low-carbohydrate diets: a systematic review. JAMA 2003; 289 (14): 183 7– 185 0.65. Foster, GD, Wyatt HR, Hill JO, et al. A randomized trial of a low-carbohydrate ... retention of these particles and accumulation of highly atherogenic partially lipolyzed cholesterol-enriched intermediate-density lipoprotein (IDL) remnants and small dense LDL particles (26– 28) ....
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Diagnosis and Management of Pituitary Disorders - part 4 potx

Diagnosis and Management of Pituitary Disorders - part 4 potx

... effectiveness of both agents (85 ,86 ), and are thought to improve compliance and reduce the cost of treatment.The effect of sulfonylureas on lipid profile components is slightly positive or neutral (82 ,87 ). ... C-reactive protein, soluble CD40 ligand, and plasmamonocyte chemoattractant protein-1 (MCP-1) (46,47,57, 58) , and 5) enhance fibrinolysis by decreasing plasmaplasminogen activator inhibitor-1 ... inhibitor-1 (PAI-1) (59,60). All of these actions are beneficial from a cardiovascular stand-point and should translate into an improved risk of mortality and cardiovascular disease-associated morbidity.The...
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Diagnosis and Management of Pituitary Disorders - part 5 docx

Diagnosis and Management of Pituitary Disorders - part 5 docx

... Periodontol1997; 68( 8):713–19.111. Chen M-K, Wen Y-S, Chang C-C, Lee H-S, Huang M-T, Hsiao H-C. Deep neck infections in diabetic patients. Am J Otolaryngol2000;21(3):169.112. Huang T-T, Tseng F-Y, Liu T-C, ... twice-, orthrice-daily dosing with biphasic insulin aspart 70/30 (The 1-2 -3 Study. Diabetes Obes Metab 2006 ;8: 58 66.15. Janka HU, Plewe G, Riddle MC, Kliebe-Frisch C, Schweitzer MA, Yki-Jarvinen ... Inflammatory Pathway, Nitric Oxide, and the EndotheliumTNF- is implicated in inflammation, cell apoptosis and survival, cytotoxicity, production of IL-1 and IL-6, and induction of insulin resistance in...
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Diagnosis and Management of Pituitary Disorders - part 6 pps

Diagnosis and Management of Pituitary Disorders - part 6 pps

... 2 58 Goff and Cushmanover either monotherapy (79), a trial of the combination of trandolapril and verapamil showed no benefit of addingverapamil to trandolapril or even of verapamil ... OutcomeRelativeRiskReductionSHEP 88 583 5 yr 155/72* 146/ 68* Chlorthalidone Stroke 22% (ns)CVD events 34%CHD 56%Syst-Eur 89 492 2 yr 162 /82 153/ 78 Nitrendipine Stroke CV events 69%CV events 62%HOT901 501 3 yr 1 48/ 85 ... care model, Part 2.JAMA 2002; 288 :1909–1914.35. Sequist TD, Gandhi TK, Karson AS, et al. A randomized trial of electronic clinical reminders to improve quality of care for diabetes and coronary...
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Diagnosis and Management of Pituitary Disorders - part 7 docx

Diagnosis and Management of Pituitary Disorders - part 7 docx

... Drug-Eluting Stents for In-Stent RestenosisREALITY Prospective, Randomized, Multi-Center Comparison of the Cypher Sirolimus-Eluting and the Taxus Paclitaxel-Eluting Stent Systems312 Petersen and ... wound-healing techniques, and treatment of infection (unloading of the foot and administration of antibiotics). Surgical drainage and debridement are oftenrequired to resolve the infection, and ... safety, and tolerability of once-daily niacin for the treatment of dyslipidemiaassociated with type 2 diabetes: results of the assessment of diabetes control and evaluation of the efficacy of niaspan...
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Diagnosis and Management of Pituitary Disorders - part 9 potx

Diagnosis and Management of Pituitary Disorders - part 9 potx

... insulin-like growth factor-1 (IGF-1) may also be effectivein lowering glucose and HbA1c levels in CGL patients (81 ).DIABETES OWING TO GENETIC DISORDERS OF -CELL FUNCTIONMaturity-Onset Diabetes of ... Endocrinol Metab 2004 ;89 : 383 5– 384 0.92. Ortega-Gonzalez C, Luna S, Hernandez L, et al. Responses of serum androgen and insulin resistance to metformin and pioglitazonein obese, insulin-resistant women ... for the diagnosis of melancholia. Standardization, validation, and clinical utility. Arch Gen Psychiatry 1 981 ; 38: 15–22.25. Linkowski P, Mendlewicz J, Kerkhofs M, et al. 24-hour profiles of adrenocorticotropin,...
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Diagnosis and Management of Pituitary Disorders - part 10 potx

Diagnosis and Management of Pituitary Disorders - part 10 potx

... 2003; 78: 7 28 733. 86 . McCarty MF. A chlorogenic acid-induced increase in GLP-1 production may mediate the impact of heavy coffee consumption ondiabetes risk. Med Hypotheses 2005;64 :84 8 85 3. 87 . ... (BAS), 281282 fibrates and niacin, 280281 omega-3 fatty acids, 282 statins and ezetimibe, 279genesis of, 274therapy benefits, 236–237EEarly Diabetes Intervention Program (EDIP), 78 79Early ... (Assessment of Diabetes Control and Evaluation of the Efficacy of NiaspanTrial) was a 16-wk, multicenter, double-blind, placebo-controlled, randomized trial, which assigned 1 48 patientsto 1 of 3 groups:...
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