báo cáo khoa học: "Reconsidering low-dose aspirin therapy for cardiovascular disease: a study protocol for physician and patient behavioral change" pot

... arterial disease and diabetes (POPADAD)trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheralarterial disease. ... 6:65http://www.implementationscience.com/content/6/1/65Page 3 of 6STUD Y PRO T O C O L Open AccessReconsidering low-dose aspirin therapy for cardiovascular disease: a study protocol for physician and patient behavioral ... statistical analysis.ES participated in the design of the patient activation form and helped todraft the manuscript. WP participated in the design of the study and the patient activation form...

Báo cáo khoa học: "Whole abdomen radiation therapy in ovarian cancers: a comparison between fixed beam and volumetric arc based intensity modulation" ppt

... data collection, DD performeddata collection, RS performed data collection, AF performed data collection and analysis, GN performed data collection and analysis, AC performed datacollection and ... (IMRT) for Whole Abdomen Radiotherapy (WAR) after ovarian cancer.Methods and Materials: Plans for IMRT and RA were optimised for 5 patients prescribing 25 Gy to the wholeabdomen (PTV_WAR) and ... Clivio A, Fogliata A, Vanetti E, Cozzi L: Simultaneous integratedboost radiotherapy for bilateral breast: a treatment planning and dosimetric comparison for volumetric modulated arc and fixed...

báo cáo khoa học: " Improving outpatient safety through effective electronic communication: a study protocol" docx

... analysis for task analyses and focus groups for alerts and CPOE, and provide workflow and task analysisexpertise. MS will lead the validation for alerts and CPOE,aid in the analysis phase of all ... of data analysis for the referraldomains, based on SH's analytic strategy, and provideinformatics expertise with particular emphasis on refer-rals. TD will code alert and referral transcripts. ... the study& apos;s qualitative core lead; she designed themethodological and analytic strategy for the task analyses and focus groups; she will facilitate the focus groups; leadthe data analysis...

báo cáo khoa học: "Selective intraarterial radionuclide therapy with Yttrium-90 (Y-90) microspheres for unresectable primary and metastatic liver tumors" potx

... chemotherapy for livermetastases and they had been accepted as refractory tochemotherapy. Partial hepatectomy, chemoembolization and radiofrequency ablation treatmen t had been per-formed in 2, 2 and ... vascularity were usedas inclusion and exclusion criteria. Liver reserve was eval-uated using bilirubin, aspartate transaminase (AST),alanine transaminase (ALT), a nd alkaline phosphatase(ALP) levels ... chemotherapy regimens and patient groups. For this reason, it would be an optimalapproach to make a comparison with an age, diagnosis,stage and chemotherapy matched control group. Sincein our study, ...

Báo cáo khoa học: Role of the C-terminal extension in a bacterial tyrosinase Michael Fairhead and Linda Thony-Meyer doc

... Tho¨ny-MeyerEMPA, Swiss Federal Laboratories for Materials Testing and Research, Laboratory for Biomaterials, St Gallen, SwitzerlandIntroductionTyrosinases and the related catechol oxidases (collec-tively ... Molecularproperties and kinetic characterization of soluble and membrane-bound forms. J Agric Food Chem 55,10446–10451.31 Gandia-Herrero F, Garcia-Carmona F & Escribano J(2004) Puriﬁcation and ... Leu WM, Wang KT & Lee YH (1992)Copper transfer and activation of the Streptomycesapotyrosinase are mediated through a complexformation between apotyrosinase and its trans-activatorMelC1....

Báo cáo khoa học: Purine nucleoside phosphorylases from hyperthermophilic Archaea require a CXC motif for stability and folding pot

... incu-bated for 22 h at 30 °C in the presence ofvarious oxidative folding catalysts (reactiva-tion assay). The catalytic activity of (A) SsM-TAPII and SsMTAPIIC259S ⁄ C261S and (B)PfPNP and ... motif for stability and foldingGiovanna Cacciapuoti, Iolanda Peluso, Francesca Fuccio and Marina PorcelliDepartment of Biochemistry and Biophysics ‘F. Cedrangolo’, Second University of Naples, ... CXC-pep-tide, and sRNaseA (0.5 mgÆmL)1in 10 mm acetic acid; ﬁnalconcentration 19.6 lm). cCMP at a ﬁnal concentration of4mm was then added and A 296, as a result of RNase-cata-lyzed cCMP...

Báo cáo khoa học: The modulation of metal bio-availability as a therapeutic strategy for the treatment of Alzheimer’s disease pptx

... Furthermore, an increase in extracellular metalscan catalyse Ab oligomerization and aggregation, and the amyloid plaques that subsequently form may thenexacerbate intracellular metal deﬁciency by ... and Fe, considerable data indi-cates a loss of Zn homeostasis in AD. Abnormallyhigh concentrations of Zn are associated with amyloidplaques in AD brain [17,37,38] and AD Tg mice [39].In a ... olig-omerization, aggregation and ﬁbrilization that Abforms amyloid plaques. As amyloid plaques are prom-inent in the postmortem AD brain, early research the-ories placed the accumulation of extracellular,insoluble...

Báo cáo khoa học: Weak toxin WTX from Naja kaouthia cobra venom interacts with both nicotinic and muscarinic acetylcholine receptors potx

... and water ad libitum.Membrane preparationsAdrenal membranes were obtained as described previously[44]. The procedure was performed in a cold room, and alllabware was washed with 1 mm EDTA ... WTX accumulated in the adrenal gland, and this organ was selected for further analysis. NeuronalnAChRs of various types (including a7 ), mAChRs,adrenoreceptors and some neuropeptide receptors areknown ... 647–655.19 Maneu V, Roje J, Mulet J, Valor ML, Sala F, CriadaM, Garcia AG & Candia L (2002) A single neuronalacetylcholine receptor a3 a7b4* is present in bovinechromafﬁn cells. Ann NY Acad Sci...

Báo cáo khoa học: Substrate recognition by three family 13 yeast a-glucosidases Evaluation of deoxygenated and conformationally biased isomaltosides pptx

... smallest for t he6¢-deoxy ana log and largest for the 2¢-deoxy analog, whileintermediary losses in activity for 3¢ -and4 ¢-deoxy analogsdid show small variations among the enzymes (Table 1). For ... Cloning of maltase genefrom a methylotrophic yeast, Hansenula polymorpha. Gene 265,77±85.19. Nakamura ,A. ,Nishimura,I.,Yokoyama ,A. ,Lee,D.G.,Hidaka,M.,Masaki, H., Kimura, A. , Chiba, S. & Uozumi, ... The Carbo hydrate-active EnzymeServer, available from http://afmb.cnrs-mrs.fr/CAZ Y/28. Yoshikawa, K., Yamamoto, K. & Okada, S. (1994) Classi®cationof some a- glucosidases and a- xylosidases...

báo cáo khoa học: " The public health utility of genome-wide association study results for smoking behavior" docx

... [9]. To translate into a clinically valid marker, a risk factor has to be very strongly asso-ciated with a trait. Ware [10] demonstrated that even a marker with an odds ratio as high as 3.58 ... perform well as a predictive test for individual patients. Although we evaluated CPD as a quantitative variable in the GWAS meta-analysis [2], the observed eﬀect size was not suﬃ -ciently large. ... optimal dose and duration of treatment. So far, pharmacogenetic trials of smoking cessation suggest that genetic variation in nicotine metabolizing enzymes and dopamine and opioid pathways may...

Xem thêm