báo cáo khoa học: "Apoptosis in cancer: from pathogenesis to treatment Rebecca SY Wong" pps

Tài liệu Báo cáo khoa học: Enzyme kinetics informatics: from instrument to browser pdf

... shown at the bottom.N. Swainston et al. Enzyme kinetics: from instrument to browser FEBS Journal 277 (2010) 37693779 ê 2010 The Authors Journal compilation ê 2010 FEBS 3775 laboratories worldwide ... Fujimoto EK, GoekeNM, Olson BJ & Klenk DC (1985) Measurement ofprotein using bicinchoninic acid. Anal Biochem 150 ,76–85.N. Swainston et al. Enzyme kinetics: from instrument to browser FEBS ... Enzyme kinetics informatics: from instrument to browser Neil Swainston1,*, Martin Golebiewski2,*, Hanan L. Messiha1, Naglis...

Tài liệu Báo cáo khoa học: Changes in purine speciﬁcity in tandem GAF chimeras from cyanobacterial cyaB1 adenylate cyclase and rat phosphodiesterase 2 pptx

... Linder et al. Cyclic nucleotide speciﬁcity in GAF domainsFEBS Journal 27 4 (20 07) 15141 523 ê 20 07 The Authors Journal compilation ê 20 07 FEBS 1 523 Changes in purine speciﬁcity in tandem GAF chimeras from ... (Ser419 in rPDE2) inter-acts with N7 and the N6amino group. The inter-actions of the b2–b3 element with the purine appear tobe rather distinct in rPDE2 GAF B, cyaB2 GAF A and cyaB2 GAF B (Fig. ... ligated. Chimeras between the C-terminal cyaB1 AC and theN-terminal rPDE2A tandem GAF domain, which carriedcorresponding inserts of the cyaB1 tandem GAF domain(constructs XII–XIV) were generated...

Tài liệu Báo cáo khoa học: "ISSUES IN NATURAL LANGUAGE ACCESS TO DATABASES FROM A LOGIC PROGRAMMING PERSPECTIVE" doc

... ISSUES IN NATURAL LANGUAGE ACCESS TO DATABASES FROM A LOGIC PROGRAMMING PERSPECTIVE David H D Warren Artificial Intelligence Center SRI International, Menlo Park, CA 94025, USA I INTRODUCTION ... permits data to be defined by general rules having the power of a fully general programming language. The logic programming approach therefore allows one to interface NL to general programs as well ... as to databases. Current Prolog systems, because they were designed with programming not databases in mind, are not capable of accommodating really large databases. However there seems to...

Tài liệu Báo cáo khoa học: "Arabic Syntactic Trees: from Constituency to Dependency" ppt

... conversion of phrase struc-tures into dependency structures is describedclearly in Xia and Palmer (2001) as (a) mark the184 Arabic Syntactic Trees: from Constituency to DependencyZdeneli ‘iabokrtskST ... parties intend to share the resourcesthey create. Prior to this exchange, 10,000 words from the LDC Arabic Newswire A Corpus weremanually annotated in both syntactic styles as astep to ensure that ... translating the topologyof a phrase tree into a corresponding de-pendency tree, and (ii) a procedure as-signing analytical functions to the nodesof the dependency tree.Apart from an outline...

Báo cáo khoa học: The in vitro effects of CRE-decoy oligonucleotides in combination with conventional chemotherapy in colorectal cancer cell lines potx

... CRE-decoys in colorectal cancer cells (Eur. J. Biochem. 271) 2781 The in vitro effects of CRE-decoy oligonucleotides in combination with conventional chemotherapy in colorectal cancer cell lines Wai ... whichtogether suggests a more profound interaction. The aims of the present study were threefold: ﬁrst, toexplore the in vitro effects of CDO alone in a panel of three colorectal cancer cell lines; ... effect of combining CDO with the chemotherapeutic drugs 5-FU, SN38 and etoposide in the two CDO-sensitive cell lines. There was neitherenhancement of cell death nor a greater reduction in the number...

Báo cáo khoa học: Nigrocin-2 peptides from Chinese Odorrana frogs – integration of UPLC/MS/MS with molecular cloning in amphibian skin peptidome analysis pot

... residues in (A) nigrocin-2- related peptides from O. sch-mackeri skin, (B) nigrocin-2- related peptides from O. grahami skin, and (C,D) identical nigrocin-2- related peptides from O. grahami skin with ... Odorrana frogs – integration of UPLC/MS/MS with molecular cloning in amphibian skin peptidome analysis Lei Wang1, Geisa Evaristo2, Mei Zhou1, Martijn Pinkse2,4, Min Wang1, Ying Xu1, Xiaofeng ... feature of nigrocin-2 peptides is reminiscent of the glycine ⁄ leucine-richdermaseptin orthologues from the skins of neotropicalphyllomedusine leaf frogs, named plasticins [30]. Nigrocin-2 peptides...

Báo cáo khoa học: Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics pptx

... failed to increase BIM expression, the combination of PD0325901 and rapa-mycin was more effective than PD0325901 alone, and death arising from the combination therapy was atleast partially BIM- dependent ... oncoprotein [56]. The mutant BCR–ABL tyro-sine kinase activates several signalling pathways, includ-ing the ERK1 ⁄ 2 pathway, the PKB pathway and theJanus kinase ⁄ signal transducer and activator of ... role of BIM as a mediator of tumour cell death in response to novel oncogene-targeted therapeutics. AbbreviationsAML, acute myeloid leukaemia; b-TrCP, b-transducin repeat containing protein; BAD,...

Báo cáo khoa học: An orphan dermaseptin from frog skin reversibly assembles to amyloid-like aggregates in a pH-dependent fashion pptx

... Gharibyan AL, Zamotin V, Yanamandra K, MoskalevaOS, Margulis BA, Kostanyan IA & Morozova-RocheLA (2007) Lysozyme amyloid oligomers and ﬁbrilsinduce cellular death via different apoptotic ... An orphan dermaseptin from frog skin reversibly assembles to amyloid-like aggregates in a pH-dependent fashion Ruth Goăòler-Schoăfberger1,Guănter Hesser2, Martin Muik3, Christian ... anti-bacterial or cytotoxic activity. We discovered that aDrscan form amyloid-like aggregates at acidic pH. Wetested the antibacterial or cytotoxic activity of these aggregates with the aim of obtaining...

Báo cáo khoa học: Ixocarpalactone A isolated from the Mexican tomatillo shows potent antiproliferative and apoptotic activity in colon cancer cells pot

... weused acridine orange ⁄ ethidium bromide staining and DAPI staining and found a marked increase in the per-centage of apoptotic cells in SW480 cells exposed toIxoA for 24 h. Additional apoptotic ... [26,27],brassinin [28,29], and deguelin [30,31]. Resveratrol ispresent in grapes, red wine and peanuts, brassinin is from Chinese cabbage, and deguelin is from an Afri-can plant, Mundule sericea. The ... summary, the data reveal that IxoA shows potent antiproliferative and apoptosis activity in human colon cancer cells. The evidence presented here suggests for the ﬁrst time that IxoA present in tomatillos...

Báo cáo khoa học: "Improvements in Analogical Learning: Application to Translating multi-Terms of the Medical Domain" pptx

... terminologies from dif-ferent domains, varying the size of the trainingmaterial. Second, analyzing the segmentation in- duced by analogical learning would be interesting.Third, we need to address ... Computational LinguisticsImprovements in Analogical Learning: Application to Translating multi-Terms of the Medical DomainPhilippe LanglaisDIROUniv. of Montreal, Canadafelipe@iro.umontreal.caFrancáois ... by analogical learn-ing. We evaluate our analogical engine on the task of translating terms of the medical domain; a do-main well-known for its tendency to create newwords, many of which being...

Báo cáo khoa học: " Apoptosis in Vero cells infected with Akabane, Aino and Chuzan virus" pot

... ...

báo cáo khoa học: "Differences in adaptive abilities of three breeds of Chinese pigs." pps

... in ACTH and glucocorticoidlevels in immature pigs of the European breeds Pietrain and Large White (MORMHDE Differences in adaptive abilities of three breeds of Chinese ... axis maybe involved in determining the differences observed in selected breeds or lines. The adaptive significance of such inter-breed variations in endocrine activities ... in adaptive abilities by studying both behavioural and neuroendocrineresponses to psychological stressor of three breeds of Chinese pigs recently introduced in France. Pigs...

báo cáo khoa học: "Apoptosis in cancer: from pathogenesis to treatment Rebecca SY Wong" pps

... Fuke H, Inoue T, Miyashita K, Yamanaka Y, Saitou Y,Sugimoto K, Nakano T: Targeting of X-linked inhibitor of apoptosisprotein or Survivin by short interfering RNAs sensitises hepatoma cells to TNF-related ... anti-apoptoticproteins that determines whether apoptosis would beinitiated [27]. O ther apoptotic factors that are released from the mitochondrial intermembrane space into thecytoplasm include ... cellularcolony growth in human cancer cells, which was found to be due to the induction of apoptosis [48].3.1.3 Inhibitor of apoptosis proteins (IAPs)The inhibitor of apoptosis proteins are a group...

báo cáo khoa học: "Updates in non-small cell lung cancer - insights from the 2009 45th annual meeting of the American Society of Clinical Oncology" potx

... (Meeting Abstracts) 2009, 27(15S):8004.doi: 10.1186/175 6-8 72 2-3 -1 8Cite this article as: Mirshahidi and Hsueh, Updates in non-small cell lung cancer - insights from the 2009 45th annual meeting ... Karnicka-Mlodkowski H, Pesek M, Serwatowski P, et al.: Phase III Study of Erlotinib in Combination With Cisplatin and Gemcitabine in Advanced Non-Small- Cell Lung Cancer: The Tarceva Lung Cancer Investigation ... trial of erlotinib in advanced non-small cell lung cancer (NSCLC) patients (p) with mutations in the tyrosine kinase (TK) domain of the epidermal growth factor receptor (EGFR). J Clin Oncol (Meeting...

Báo cáo khoa học: "Lactate in the intensive care unit: pyromaniac, sentinel or fireman" pps

... online http://ccforum.com/content/9/6/622Although there is no doubt about the fact that a change in lactate metabolism is linked to energy imbalance, the completepicture of the mechanisms involved ... adaptive for a fall in mitochondrial (aerobic) ATP supply only when associated witha decrease in ATP consumption, imposing a new hierarchicalsetting on the different ATP consuming pathways. In otherwords, ... consideredthat rises in lactate also occur frequently in the absence ofacidosis, or even simultaneously with alkalosis. Indeed, severalcauses of hyperlactatemia encountered in intensive care unitpatients...

Xem thêm