... uncertainties must be borne in mind
during the independent peer review of the preclinical
data. Only when the compelling preclinical data are
available, careful and incremental testing in patients ... basing on their clinical applications, and taking into
account the ethical issue associated with the stem cell therapy.
Methods: We have searched Pubmed/Medline for clinical trial...
... expression of secreted protein acid rich in
cysteine (SPARC) and clinical outcome. This regimen is
currently being investigated in a randomized phase III
study.
Promising results were also reported ... using the
nanoparticle formulations. I nsulin-like growth factor 1
receptor (IGF1R) targeted antibodies and tyrosine kinase
inhibitors are being investigated in a variety of tumor
t...
... developing
guidelines in the first place.
Comparing guidelines released and included in the CMA
Infobase from 1994–1999 and 2000–2005, revealed that
100 fewer guidelines were deposited in the CMA Infobase
in ... doing what." Surveying guideline
developers about their processes of guideline develop-
ment and implementation and doing so over time, offers
a unique glimpse i...
... Pressler BM, Lappin MR, Jensen WA: Effects of urinary
tract inflammation and sample blood contamination on
urine albumin and total protein concentrations in canine
urine samples. Vet Clin Pathol 2004, ... sclerosis and proteinuria in the dog remains to
be defined.
Increasing amounts of interstitial fibrosis and age-associ-
ated glomerular sclerosis has been described in people
[...
... gland-submaxillary/lingual
Harderian gland
a
Seminal vesicles
Heart Yes Skin
Intestine-duodenum Spleen
a
Yes
Intestine-jejunum Spinal cord-lumbar and cervical
Intestine-ileum Stomach
Intestine-colon Testes Yes
Intestine-caecum ... dehydrated,
embedded in paraffin and cut into 4 μm sections before
they were stained with haematoxylin and eosin for micro-
scopic evaluation.
Clinical pa...
... are of limited
relevance to the clinical setting. Clinical studies produced
controversial results. NAC treatment during the first hours of
severe clinical sepsis and septic shock decreased peroxidative
Commentary
N
-acetylcysteine ... properties to the clinical test remain
scarce but are definitely needed to determine whether N-acetylcysteine has a place in our therapeutic
armamen...
... P
i
released min
)1
Æmg
)1
of protein.
Enzyme kinetic study
The K
m
(Michaelis constant) and V
max
(maximum velocity)
values were determined by incubating the diluted recombin-
ant proteins in the standard ... deparaffinized and
dehydrated using a graded series of alcohol and then
rehydrated in NaCl/P
i
. The slides were blocked for 30 min
in 1% H
2
O
2
in NaCl/P
i
containing 10%...
...
bootstrapping. It includes co-training (Blum and
Mitchell, 1998; Collins and Singer, 1998; Nigam
and Ghani, 2000) and bilingual bootstrapping (Li
and Li, 2002).
Collaborative bootstrapping begins ... unlabeled training
and test data sets. We used 3 texts per class as la-
belled instances for training, 994 texts for testing,
and the remaining 1000 texts as unlabelled in-
s...
... im-
plementing lexical morphology principles in a
machine translation system in order to solve
unknown words. Multilingual symbolic treat-
ment of word-formation is seducing but re-
quires an in- depth ... example, the
routine is able to find links between adjectives
and base nouns such as ambientale and ambiente,
aziendale and azienda, cortisonica and cortisone
or contestua...