... matrix metallopro-teinases and tissue inhibitors of metalloproteinases in anky-losing spondylitis: MMP-3 is a reproducibly sensitive and specific biomarker of disease activity. Rheumatology ... 26:2201-2204.29. Vandooren B, Kruithof E, Yu DT, Rihl M, Gu J, De Rycke L, BoschF Van Den, Veys EM, De Keyser F, Baeten D: Involvement of matrix metalloproteinases and their inhibitors in peripheralsynovitis ... time in the case of MMP-3 serum levels. A longitu-dinal study of VEGF and BALP serum levels during an obser-vation period of 2 years was not reported before, but stableserum levels of VEGF and...