Báo cáo y học: "Intraperitoneal Alpha-Lipoic Acid to prevent neural damage after crush injury to the rat sciatic nerve" docx
Báo cáo y học: "Intraperitoneal Alpha-Lipoic Acid to prevent neural damage after crush injury to the rat sciatic nerve" docx
... Brachial Plexus and Peripheral Nerve Injury Open AccessResearch articleIntraperitoneal Alpha-Lipoic Acid to prevent neural damage after crush injury to the rat sciatic nerveMehmet Senoglu*1, ... h before the crush injury. Weaimed to investigate the early effects of antioxidant ther-apy with a-LA. In Group I, sciatic nerve was explorated butnot crushed. Sciatic nerve injury was induced ... poisoning,heavy metal intoxication and diabetic polyneuropathy[22]. The SOD-CAT system provides the first defense againstoxygen toxicity. SOD catalyzes the dismutation of the superoxide anion radical to...
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Báo cáo y học: " Isolated radial head dislocation, a rare and easily missed injury in the presence of major distracting injuries: a case report" ppsx
... frac-ture but no other bony injuries were identified. Stressviews of the knees in theatre revealed ligamentous laxitybilaterally. The pelvis was stabilised with an external fixa-tor after initial ... to bothknees.12 hours later, the patient complained of pain in the rightelbow. There was no previous history of elbow injury orarthritis. On examination, there was minimal swellingover the ... degenerative arthritisof the elbow and the distal radioulnar joints.ConclusionThis case report has been prepared to stress the impor-tance of a thorough secondary survey in patients with pol-ytrauma...
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Báo cáo y học: "Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254)" ppt
... likely cause of this observed early cartilageand joint damage after acute injury is through the effectof pro-inflammatory cytokines released into the synovialfluid. This observed inflammatory ... is may constitute new treatmentstrategies to prevent the irreversible cartilage damage intheformofcollagenlossafteracuteinjuryandtherebyoffer the hope of preventing future onset of injury related ... incartilage explant systems could be directly translated to the treatment of acute injury to reduce or even prevent early cartilage damage, thereby potentially reducing the risk of later early onset OA.AbbreviationsADAMTS:...
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Báo cáo y học: "Optimization of 5-fluorouracil solid-lipid nanoparticles: a preliminary study to treat colon cancer"
... 399 for the local delivery of a high concentration of active agents in the colon to improve pharmacotherapy and reduce its potential systemic toxicity and side effects [3]. The early detection, ... drug therapy [4-6]. Nanoparticles have extraordinary physical and chemical properties resulting from the nanosize effect [7]. They play an important role in cancer therapy to detect or to deliver ... the same composition. Briefly, F8 composed of drug to lipid at 1:4 ratio and soyalithicin to Dynasan114 at 2:1 ratio (stabilized by 0.5% PVA) is considered the op-timum formula for the Dynasan...
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Báo cáo y học: " Carotid Intima-media thickness in childhood and adolescent obesity relations to abdominal obesity, high triglyceride level and insulin resistance"
... alterations in carotid inti-ma-media thickness in the moderately hypercholesterolaemic hypertensive patients of the Plaque Hypertension Lipid Lo-wering Italian Study. PHYLLIS study group. J Hypertens. ... were made in the longitudinal plane at the point of maximum thickness on the far wall of the common carotid artery along a 1 cm sec-tion of the artery proximal to the carotid bulb. The IMT was ... measured at the midway be-tween the lower rib and the iliac crest, hip circumfe-rence was measured at the widest part at the gluteal region. Systolic blood pressure (SBP) and diastolic blood...
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Báo cáo y học: "Weight loss, leukopenia and thrombocytopenia associated with sustained virologic response to Hepatitis C treatmen"
... responded well to the therapy and these side effects, if not severe, may not be indications for withholding or reducing the dose of the treat-ment. We hypothesized that the greater cytopenia is ... During the period of study, 78 pa-tients started on therapy. Twenty four patients were not included in the study analysis due to fail to com-plete treatment and evaluation. Of these, 13 failed to ... 24 weeks after the end of therapy. Inter-feron dosing was not adjusted but ribavirin occasion-ally was. Hematology growth factors were occasion-ally used but not consistently. Study design...
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Báo cáo y học: "Comparison of a Two-Lead, Computerized, Resting ECG Signal Analysis Device, the MultiFunction-CardioGramsm or MCG (a.k.a. 3DMP), to Quantitative Coronary Angiography for the Detection of Relevant Coronary Artery Stenosis (70%)
... locally recorded, but remotely analyzed at a central US data facility, due to the size and complexity of the digital signal process-ing, the analysis by multiple mathematic functions, and the ... according to whether the patients had prior revascularization. The boundaries of the box are Tukey’s hinges. The median is identified by the line inside the box. The length of the box is the interquartile ... 27.7% to 43.4%. Subjects included in the trial were ambulatory patients who presented to their physicians for evaluation. Physicians used tools commonly at their disposal, including the available...
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Báo cáo y học: Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects"
... factors necessary to the sub-sequent healing phases are generated such as growth factors and cytokines, which promote migration of in-flammatory cells, fibroblasts and endothelial cells into ... evi-dent in ophthalmology, dermatology, dentistry and rheumatology [10,11]. Based up on these data the aim of this study was to observe the potential of Esterified Hyaluronic Acid (EHA) as a coadjuvant ... were made at the buccal and lingual sides with Bard-Parker surgical blade n° 15, at least one tooth away from the mesial portion, distally to the graft site, to create access for the tools and...
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Báo cáo Y học: A new conceptual framework for enzyme catalysis Hydrogen tunneling coupled to enzyme dynamics in flavoprotein and quinoprotein enzymes docx
... increasing the catalytic efficiency of enzymes in the biotechnology industry (by enhancing the coupling ofdynamics to the reaction coordinate), and (b) producingmore effective enzyme inhibitors in the ... energy surface. Followingtunneling from donor to acceptor atoms, distortion of the active site geometry away from the optimal configurationeffectively traps the H nucleus on the product side of the barrier. ... illustrated that quantum tunneling is driven bythermal vibrations of the enzyme-substrate complex, whichserve to increase the tunneling probability (by reducing the width and/or height of the...
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Báo cáo y học: "Advanced glycation end-product (AGE)-damaged IgG and IgM autoantibodies to IgG-AGE in patients with early synovitis." ppt
... by AGE,can contribute to the inflammatory cycle by the inductionof proinflammatory cytokines, via the nuclear factor-κBpathway [21]. No studies have yet examined RAGEexpression in the synovium ... receptors for AGE, one of whichis termed receptor for AGE (RAGE) [20]. The presentstudy shows that the formation of AGE-damaged IgG inthis early synovitis cohort is linked to the inflammatoryresponse ... inflammatoryresponse rather than to hyperglycemia. The latter is key in the AGE associated with diabetes [3]. We did notmeasure hemoglobin A1c in the present study, but in aprevious study it was not found to...
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