... susceptible to PGIA and PGIS, produced thehighest levels of anti-inflammatory IL-4, proinflammatory IL-6 and IFN-γ cytokines when assayed in spleen cultures. How-ever, there was no evidence that any of ... frequently (for example, C5deficiency in DBA/2 mice [88,89], in the cytoplasmic domain of Toll-like receptor-4 of The Jackson Laboratory's C3H/HeJcolony [90], and in the Ptpn6 gene of motheaten ... we have shown, and different genes in different QTLs control PGIA [9] and PGIS[29]. Interestingly, although inflammatory (autoimmune)spondyloarthropathy occurs only in BALB/c and C3H mice[7,8,11],...